TDO2

DescriptionTryptophan 2,3-dioxygenase

Gene and Protein Information

Gene ID6999
Uniprot Accession IDs A8K053 TDO
Ensembl ID ENSP00000444788
Symbol TDO TO TDO TPH2 TRPO HYPTRP
FamilyBelongs to the tryptophan 2,3-dioxygenase family.
Sequence
MSGCPFLGNNFGYTFKKLPVEGSEEDKSQTGVNRASKGGLIYGNYLHLEKVLNAQELQSETKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVVSRMHRVSVILKLLVQQFSILETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQNMRVPYNRRHYRDNFKGEENELLLKSEQEKTLLELVEAWLERTPGLEPHGFNFWGKLEKNITRGLEEEFIRIQAKEESEEKEEQVAEFQKQKEVLLSLFDEKRHEHLLSKGERRLSYRALQGALMIYFYREEPRFQVPFQLLTSLMDIDSLMTKWRYNHVCMVHRMLGSKAGTGGSSGYHYLRSTVSDRYKVFVDLFNLSTYLIPRHWIPKMNPTIHKFLYTAEYCDSSYFSSDESD
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp736252TDO2tryptophan 2,3-dioxygenase9598VGNC:12992Inparanoid, OMA, EggNOG
Macaque699739TDO2tryptophan 2,3-dioxygenase9544OMA, EggNOG
Mouse56720Tdo2tryptophan 2,3-dioxygenase10090MGI:1928486Inparanoid, OMA, EggNOG
Rat64206Tdo2tryptophan 2,3-dioxygenase10116RGD:68370Inparanoid, OMA, EggNOG
Dog475476TDO2tryptophan 2,3-dioxygenase9615VGNC:47217Inparanoid, OMA, EggNOG
Horse100069524TDO2tryptophan 2,3-dioxygenase9796VGNC:50775Inparanoid, OMA, EggNOG
Cow530397TDO2tryptophan 2,3-dioxygenase9913VGNC:35712Inparanoid, OMA, EggNOG
Pig100301559TDO2tryptophan 2,3-dioxygenase9823OMA, EggNOG
Opossum100023852TDO2tryptophan 2,3-dioxygenase13616Inparanoid, OMA, EggNOG
Platypus100075117TDO2tryptophan 2,3-dioxygenase9258OMA, EggNOG
Anole lizard100551544tdo2tryptophan 2,3-dioxygenase28377Inparanoid, OMA, EggNOG
Xenopus548450tdo2tryptophan 2,3-dioxygenase8364XB-GENE-976712Inparanoid, OMA, EggNOG
Zebrafish100008541tdo2atryptophan 2,3-dioxygenase a7955ZDB-GENE-030131-1187OMA, EggNOG
Zebrafish334082tdo2btryptophan 2,3-dioxygenase b7955ZDB-GENE-030131-6014Inparanoid, OMA
C. elegans175836tdo-2Tryptophan 2,3-dioxygenase6239Inparanoid, OMA, EggNOG
Fruitfly32026vvermilion7227FBgn0003965Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    oxidoreductase    /    oxygenase    /    Tryptophan 2,3-dioxygenase
DTO Classes
protein    /    Enzyme    /    Oxidoreductase    /    Oxygenase    /    Tryptophan 2,3-dioxygenase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

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