SORT1

DescriptionSortilin

Gene and Protein Information

Gene ID6272
Uniprot Accession IDs B4DWI3 C0JYZ0 Q8IZ49
Ensembl ID ENSP00000256637
Symbol NT3 Gp95 NTR3 LDLCQ6
FamilyBelongs to the VPS10-related sortilin family. SORT1 subfamily.
Sequence
MERPWGAADGLSRWPHGLGLLLLLQLLPPSTLSQDRLDAPPPPAAPLPRWSGPIGVSWGLRAAAAGGAFPRGGRWRRSAPGEDEECGRVRDFVAKLANNTHQHVFDDLRGSVSLSWVGDSTGVILVLTTFHVPLVIMTFGQSKLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSGKVVLTAEVSGGSRGGRIFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENGLWVSKNFGGKWEEIHKAVCLAKWGSDNTIFFTTYANGSCKADLGALELWRTSDLGKSFKTIGVKIYSFGLGGRFLFASVMADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLSEDNSIQTMITFDQGGRWTHLRKPENSECDATAKNKNECSLHIHASYSISQKLNVPMAPLSEPNAVGIVIAHGSVGDAISVMVPDVYISDDGGYSWTKMLEGPHYYTILDSGGIIVAIEHSSRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLASEPGARSMNISIWGFTESFLTSQWVSYTIDFKDILERNCEEKDYTIWLAHSTDPEDYEDGCILGYKEQFLRLRKSSVCQNGRDYVVTKQPSICLCSLEDFLCDFGYYRPENDSKCVEQPELKGHDLEFCLYGREEHLTTNGYRKIPGDKCQGGVNPVREVKDLKKKCTSNFLSPEKQNSKSNSVPIILAIVGLMLVTVVAGVLIVKKYVCGGRFLVHRYSVLQQHAEANGVDGVDALDTASHTNKSGYHDDSDEDLLE
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque698310SORT1sortilin 19544Inparanoid, OMA, EggNOG
Mouse20661Sort1sortilin 110090MGI:1338015Inparanoid, OMA, EggNOG
Rat83576Sort1sortilin 110116RGD:619999Inparanoid, OMA, EggNOG
Dog479915SORT1sortilin 19615VGNC:46664Inparanoid, OMA, EggNOG
Horse100061385SORT1sortilin 19796VGNC:23453Inparanoid, OMA, EggNOG
Cow511591SORT1sortilin 19913VGNC:35133Inparanoid, OMA, EggNOG
Pig106504120SORT1sortilin 19823Inparanoid, OMA
Opossum100033052SORT1sortilin 113616Inparanoid, OMA, EggNOG
Anole lizard100561957sort1sortilin 128377Inparanoid, OMA, EggNOG
Xenopus100490074sort1sortilin 18364XB-GENE-982637Inparanoid, OMA, EggNOG
Zebrafish406511sort1asortilin 1a7955ZDB-GENE-040426-2329OMA, EggNOG
Zebrafish799153sort1bsortilin 1b7955ZDB-GENE-030131-7447Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    Sortilin
protein    /    receptor    /    Sortilin
DTO Classes
protein    /    Transporter    /    Sortilin

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source