TRHDE

DescriptionThyrotropin-releasing hormone-degrading ectoenzyme

Gene and Protein Information

Gene ID29953
Uniprot Accession IDs A5PL19 Q6UWJ4 TRH-DE
Ensembl ID ENSP00000261180
Symbol PAP-II PGPEP2 TRH-DE
FamilyBelongs to the peptidase M1 family.
Sequence
MGEDDAALRAGSRGLSDPWADSVGVRPRTTERHIAVHKRLVLAFAVSLVALLAVTMLAVLLSLRFDECGASATPGADGGPSGFPERGGNGSLPGSARRNHHAGGDSWQPEAGGVASPGTTSAQPPSEEEREPWEPWTQLRLSGHLKPLHYNLMLTAFMENFTFSGEVNVEIACRNATRYVVLHASRVAVEKVQLAEDRAFGAVPVAGFFLYPQTQVLVVVLNRTLDAQRNYNLKIIYNALIENELLGFFRSSYVLHGERRFLGVTQFSPTHARKAFPCFDEPIYKATFKISIKHQATYLSLSNMPVETSVFEEDGWVTDHFSQTPLMSTYYLAWAICNFTYRETTTKSGVVVRLYARPDAIRRGSGDYALHITKRLIEFYEDYFKVPYSLPKLDLLAVPKHPYAAMENWGLSIFVEQRILLDPSVSSISYLLDVTMVIVHEICHQWFGDLVTPVWWEDVWLKEGFAHYFEFVGTDYLYPGWNMEKQRFLTDVLHEVMLLDGLASSHPVSQEVLQATDIDRVFDWIAYKKGAALIRMLANFMGHSVFQRGLQDYLTIHKYGNAARNDLWNTLSEALKRNGKYVNIQEVMDQWTLQMGYPVITILGNTTAENRIIITQQHFIYDISAKTKALKLQNNSYLWQIPLTIVVGNRSHVSSEAIIWVSNKSEHHRITYLDKGSWLLGNINQTGYFRVNYDLRNWRLLIDQLIRNHEVLSVSNRAGLIDDAFSLARAGYLPQNIPLEIIRYLSEEKDFLPWHAASRALYPLDKLLDRMENYNIFNEYILKQVATTYIKLGWPKNNFNGSLVQASYQHEELRREVIMLACSFGNKHCHQQASTLISDWISSNRNRIPLNVRDIVYCTGVSLLDEDVWEFIWMKFHSTTAVSEKKILLEALTCSDDRNLLNRLLNLSLNSEVVLDQDAIDVIIHVARNPHGRDLAWKFFRDKWKILNTRYGEALFMNSKLISGVTEFLNTEGELKELKNFMKNYDGVAAASFSRAVETVEANVRWKMLYQDELFQWLGKALRH
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp467071TRHDEthyrotropin releasing hormone degrading enzyme9598VGNC:8586OMA, EggNOG
Macaque717653TRHDEthyrotropin releasing hormone degrading enzyme9544Inparanoid, OMA, EggNOG
Mouse237553TrhdeTRH-degrading enzyme10090MGI:2384311Inparanoid, OMA, EggNOG
Rat366894Trhdethyrotropin-releasing hormone degrading enzyme10116RGD:728895Inparanoid, OMA, EggNOG
Dog481166TRHDEthyrotropin releasing hormone degrading enzyme9615VGNC:47798Inparanoid, OMA, EggNOG
Horse100057250TRHDEthyrotropin releasing hormone degrading enzyme9796VGNC:24489Inparanoid, OMA, EggNOG
Cow100336818TRHDEthyrotropin releasing hormone degrading enzyme9913VGNC:36305Inparanoid, OMA, EggNOG
Pig100620702TRHDEthyrotropin releasing hormone degrading enzyme9823Inparanoid, OMA, EggNOG
Opossum100016797TRHDEthyrotropin releasing hormone degrading enzyme13616Inparanoid, OMA, EggNOG
Chicken427868TRHDEthyrotropin releasing hormone degrading enzyme9031CGNC:7757Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    metalloprotease    /    Thyrotropin-releasing hormone-degrading ectoenzyme
DTO Classes
protein    /    Enzyme    /    Protease    /    Metalloprotease    /    Thyrotropin-releasing hormone-degrading ectoenzyme

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source