F2

DescriptionProthrombin

Gene and Protein Information

Gene ID2147
Uniprot Accession IDs B2R7F7 B4E1A7 Q4QZ40 Q53H04 Q53H06 Q69EZ7 Q7Z7P3 Q9UCA1
Ensembl ID ENSP00000308541
Symbol PT THPH1 RPRGL2
FamilyBelongs to the peptidase S1 family.
Sequence
MAHVRGLQLPGCLALAALCSLVHSQHVFLAPQQARSLLQRVRRANTFLEEVRKGNLERECVEETCSYEEAFEALESSTATDVFWAKYTACETARTPRDKLAACLEGNCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTGPWCYTTDPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDEEGVWCYVAGKPGDFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWRENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQFGE
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp451158F2coagulation factor II, thrombin9598VGNC:7501OMA, EggNOG
Macaque712729F2coagulation factor II, thrombin9544Inparanoid, OMA, EggNOG
Mouse14061F2coagulation factor II10090MGI:88380Inparanoid, OMA, EggNOG
Rat29251F2coagulation factor II10116RGD:61996Inparanoid, OMA, EggNOG
Dog100856539F2coagulation factor II, thrombin9615VGNC:40547Inparanoid, OMA, EggNOG
Horse100057521F2coagulation factor II, thrombin9796VGNC:17757Inparanoid, OMA, EggNOG
Cow280685F2coagulation factor II, thrombin9913VGNC:28682Inparanoid, OMA, EggNOG
Pig100144442F2coagulation factor II, thrombin9823Inparanoid, OMA, EggNOG
Chicken395306F2coagulation factor II, thrombin9031CGNC:6314Inparanoid, OMA, EggNOG
Anole lizard100566916f2coagulation factor II, thrombin28377Inparanoid, OMA, EggNOG
Xenopus548514f2coagulation factor II, thrombin8364XB-GENE-481539Inparanoid, OMA, EggNOG
Zebrafish325881f2coagulation factor II (thrombin)7955ZDB-GENE-030131-4606Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    serine protease    /    Prothrombin
protein    /    protease    /    Prothrombin
protein    /    hydrolase    /    Prothrombin
DTO Classes
protein    /    Enzyme    /    Protease    /    Serine protease    /    Prothrombin

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source