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TIE1
| Description | Tyrosine-protein kinase receptor Tie-1 |
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Gene and Protein Information
| Gene ID | 7075 |
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| Uniprot Accession IDs | B5A949 B5A950 |
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| Ensembl ID | ENSP00000361554 |
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| Symbol | TIE TIE JTK14 |
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| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. Tie subfamily. |
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| Sequence | MVWRVPPFLLPILFLASHVGAAVDLTLLANLRLTDPQRFFLTCVSGEAGAGRGSDAWGPPLLLEKDDRIVRTPPGPPLRLARNGSHQVTLRGFSKPSDLVGVFSCVGGAGARRTRVIYVHNSPGAHLLPDKVTHTVNKGDTAVLSARVHKEKQTDVIWKSNGSYFYTLDWHEAQDGRFLLQLPNVQPPSSGIYSATYLEASPLGSAFFRLIVRGCGAGRWGPGCTKECPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGISGCRGLTFCLPDPYGCSCGSGWRGSQCQEACAPGHFGADCRLQCQCQNGGTCDRFSGCVCPSGWHGVHCEKSDRIPQILNMASELEFNLETMPRINCAAAGNPFPVRGSIELRKPDGTVLLSTKAIVEPEKTTAEFEVPRLVLADSGFWECRVSTSGGQDSRRFKVNVKVPPVPLAAPRLLTKQSRQLVVSPLVSFSGDGPISTVRLHYRPQDSTMDWSTIVVDPSENVTLMNLRPKTGYSVRVQLSRPGEGGEGAWGPPTLMTTDCPEPLLQPWLEGWHVEGTDRLRVSWSLPLVPGPLVGDGFLLRLWDGTRGQERRENVSSPQARTALLTGLTPGTHYQLDVQLYHCTLLGPASPPAHVLLPPSGPPAPRHLHAQALSDSEIQLTWKHPEALPGPISKYVVEVQVAGGAGDPLWIDVDRPEETSTIIRGLNASTRYLFRMRASIQGLGDWSNTVEESTLGNGLQAEGPVQESRAAEEGLDQQLILAVVGSVSATCLTILAALLTLVCIRRSCLHRRRTFTYQSGSGEETILQFSSGTLTLTRRPKLQPEPLSYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLKMNAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRFASDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSRGEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFAQIALQLGRMLEARKAYVNMSLFENFTYAGIDATAEEA Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 469308 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 9598 | VGNC:7007 | OMA, EggNOG |
| Macaque | 702208 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 21846 | Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 10090 | MGI:99906 | Inparanoid, OMA, EggNOG |
| Rat | 89806 | Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 10116 | RGD:621642 | Inparanoid, OMA, EggNOG |
| Dog | 482535 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 9615 | VGNC:47366 | Inparanoid, OMA, EggNOG |
| Horse | 100066563 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 9796 | VGNC:24101 | Inparanoid, OMA, EggNOG |
| Cow | 280941 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 9913 | VGNC:35861 | Inparanoid, OMA, EggNOG |
| Pig | 494022 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 9823 | | OMA, EggNOG |
| Opossum | 100025707 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 13616 | | Inparanoid, OMA, EggNOG |
| Chicken | 424562 | TIE1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 9031 | CGNC:7566 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100565697 | tie1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 100496664 | tie1 | tyrosine kinase with immunoglobulin like and EGF like domains 1 | 8364 | XB-GENE-922217 | Inparanoid, OMA, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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