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ATP2A2

DescriptionSarcoplasmic/endoplasmic reticulum calcium ATPase 2

Gene and Protein Information

Gene ID488
Uniprot Accession IDs A6NDN7 B4DF05 P16614 Q86VJ2 SERCA2
Ensembl ID ENSP00000440045
Symbol ATP2B DD DAR ATP2B SERCA2
FamilyBelongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
Sequence
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVLLIMPLVIWVYSTDTNFSDMFWS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp452231ATP2A2ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 29598VGNC:8342OMA, EggNOG
Macaque710702ATP2A2ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 29544OMA, EggNOG
Mouse11938Atp2a2ATPase, Ca++ transporting, cardiac muscle, slow twitch 210090MGI:88110Inparanoid, OMA, EggNOG
Rat29693Atp2a2ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 210116RGD:2174Inparanoid, OMA
Dog403878ATP2A2ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 29615VGNC:38254Inparanoid, OMA, EggNOG
Horse791242ATP2A2ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 29796VGNC:15651Inparanoid, OMA
Cow540568ATP2A2ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 29913VGNC:26291Inparanoid, OMA
Opossum100015597ATP2A2ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 213616Inparanoid, OMA
Platypus100073740ATP2A2ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 29258Inparanoid, OMA, EggNOG
Anole lizard100554752atp2a2ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 228377Inparanoid, OMA
Xenopus100489059atp2a2ATPase, Ca++ transporting, cardiac muscle, slow twitch 28364XB-GENE-1012933Inparanoid, OMA
Zebrafish568265atp2a2bATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2b7955ZDB-GENE-030131-867Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    ion channel    /    Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
protein    /    transporter    /    cation transporter    /    Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
protein    /    transporter    /    hydrolase    /    Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
DTO Classes
protein    /    Transporter    /    P-type ATPases    /    Ca2+-ATPases    /    Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
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