| Description | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 |
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Gene and Protein Information
| Gene ID | 487 |
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| Uniprot Accession IDs | A8K5J9 B3KY17 O14984 SERCA1 |
| Ensembl ID | ENSP00000349595 |
| Symbol | ATP2A SERCA1 |
| Family | Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. |
| Sequence | MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLKISLPVIGLDEILKFVARNYLEDPEDERRK Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 454019 | ATP2A1 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 | 9598 | VGNC:9020 | OMA, EggNOG |
| Mouse | 11937 | Atp2a1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 10090 | MGI:105058 | Inparanoid, OMA, EggNOG |
| Dog | 479797 | ATP2A1 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 | 9615 | VGNC:38253 | Inparanoid, OMA |
| Horse | 100064403 | ATP2A1 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 | 9796 | VGNC:15650 | Inparanoid, OMA |
| Cow | 518117 | ATP2A1 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 | 9913 | VGNC:26290 | Inparanoid, OMA |
| Pig | 100516962 | ATP2A1 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 | 9823 | Inparanoid, OMA | |
| Anole lizard | 100554310 | atp2a1 | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 | 28377 | Inparanoid, OMA | |
| Xenopus | 613090 | atp2a1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 8364 | XB-GENE-975115 | Inparanoid, OMA |
| Zebrafish | 494489 | atp2a1l | ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like | 7955 | ZDB-GENE-041229-2 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / transporter / ion channel / Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
protein / transporter / cation transporter / Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
protein / transporter / hydrolase / Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
protein / transporter / ion channel / Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
protein / transporter / cation transporter / Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
protein / transporter / hydrolase / Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
DTO Classes
protein / Transporter / P-type ATPases / Ca2+-ATPases / Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
protein / Transporter / P-type ATPases / Ca2+-ATPases / Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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