ARHGEF12

DescriptionRho guanine nucleotide exchange factor 12

Gene and Protein Information

Gene ID23365
Uniprot Accession IDs O15086 Q6P526
Ensembl ID ENSP00000380942
Symbol KIAA0382 LARG LARG PRO2792
Sequence
MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIASHDFDPTDSSSKKTKSSSEESRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEPSVIGHMSPIMTSPHSPGASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQEAKKHIPQLQEQLSKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDASRPSSDNADSPKSGPKERIYLEENPEKSETIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGTEHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRRIFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDKSSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSILGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGYLPANSMSSVASGASFSQEGGKENDTGSKQVGETSAPGDTLDGTPRTLNTVFDFPPPPLDQVQEEECEVERVTEHGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLGLKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKVKKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKMIHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVIKLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTKPIPLPQSTPGEGDNDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTSGKSEVRDLFVAERQFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLKQLLVQQLGLTEKSVQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTGDIATCYSPRTSTESFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEHFFDAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQPMTGIPAVESTHQQQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQSQIMEYIHKIEADLEHLKKVEESYTILCQRLAGSALTDKHSDKS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp451618ARHGEF12Rho guanine nucleotide exchange factor 129598VGNC:3208OMA, EggNOG
Mouse69632Arhgef12Rho guanine nucleotide exchange factor (GEF) 1210090MGI:1916882Inparanoid, OMA, EggNOG
Rat367072Arhgef12Rho guanine nucleotide exchange factor 1210116RGD:1305111Inparanoid, OMA, EggNOG
Dog479409ARHGEF12Rho guanine nucleotide exchange factor 129615VGNC:38075Inparanoid, OMA, EggNOG
Horse100071503ARHGEF12Rho guanine nucleotide exchange factor 129796VGNC:15484Inparanoid, OMA, EggNOG
Cow503575ARHGEF12Rho guanine nucleotide exchange factor 129913VGNC:26106Inparanoid, OMA, EggNOG
Pig100523324ARHGEF12Rho guanine nucleotide exchange factor 129823Inparanoid, OMA
Opossum100030904ARHGEF12Rho guanine nucleotide exchange factor 1213616Inparanoid, OMA, EggNOG
Chicken419752ARHGEF12Rho guanine nucleotide exchange factor 129031CGNC:51082Inparanoid, OMA
Anole lizard100566171arhgef12Rho guanine nucleotide exchange factor 1228377Inparanoid, OMA
Xenopus779951arhgef12Rho guanine nucleotide exchange factor 128364XB-GENE-485387Inparanoid, OMA
Zebrafish571031arhgef12bRho guanine nucleotide exchange factor (GEF) 12b7955ZDB-GENE-070705-36Inparanoid, OMA
C. elegans184419rhgf-1RHo Guanine nucleotide exchange Factor6239Inparanoid, OMA

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

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