GRK2
| Description | Beta-adrenergic receptor kinase 1 |
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Gene and Protein Information
| Gene ID | 156 |
|---|---|
| Uniprot Accession IDs | B0ZBE1 Q13837 Q6GTT3 Beta-ARK-1 |
| Ensembl ID | ENSP00000312262 |
| Symbol | ADRBK1 BARK BARK1 BARK1 ADRBK1 BETA-ARK1 |
| Family | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. |
| Sequence | MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPRSPVVELSKVPLVQRGSANGL Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 451363 | GRK2 | G protein-coupled receptor kinase 2 | 9598 | VGNC:10432 | OMA, EggNOG |
| Macaque | 721754 | GRK2 | G protein-coupled receptor kinase 2 | 9544 | OMA, EggNOG | |
| Mouse | 110355 | Grk2 | G protein-coupled receptor kinase 2 | 10090 | MGI:87940 | Inparanoid, OMA, EggNOG |
| Rat | 25238 | Grk2 | G protein-coupled receptor kinase 2 | 10116 | RGD:2062 | OMA, EggNOG |
| Cow | 282682 | GRK2 | G protein-coupled receptor kinase 2 | 9913 | OMA, EggNOG | |
| Pig | 100513842 | GRK2 | G protein-coupled receptor kinase 2 | 9823 | OMA, EggNOG | |
| Anole lizard | 100555775 | grk2 | G protein-coupled receptor kinase 2 | 28377 | OMA, EggNOG | |
| C. elegans | 175223 | grk-2 | G protein-coupled receptor kinase 2 | 6239 | OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / non-receptor serine/threonine protein kinase / Beta-adrenergic receptor kinase 1
protein / protein kinase / Beta-adrenergic receptor kinase 1
protein / transferase / Beta-adrenergic receptor kinase 1
protein / kinase / Beta-adrenergic receptor kinase 1
protein / non-receptor serine/threonine protein kinase / Beta-adrenergic receptor kinase 1
protein / protein kinase / Beta-adrenergic receptor kinase 1
protein / transferase / Beta-adrenergic receptor kinase 1
protein / kinase / Beta-adrenergic receptor kinase 1
DTO Classes
protein / Kinase / Protein kinase / AGC group / GRK family / BARK subfamily / Beta-adrenergic receptor kinase 1
protein / Kinase / Protein kinase / AGC group / GRK family / BARK subfamily / Beta-adrenergic receptor kinase 1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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