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| Description | Histone deacetylase 8 |
|---|
Gene and Protein Information
| Gene ID | 55869 |
|---|---|
| Uniprot Accession IDs | Q9BY41 A6ND12 A6ND61 A6NET3 A6NJR3 A8MQ62 B4DKN0 B4DV22 Q86VC8 Q9NP76 Q9NYH4 HD8 |
| Ensembl ID | ENSP00000362674 |
| Symbol | HDACL1 HD8 WTS RPD3 CDA07 CDLS5 KDAC8 MRXS6 HDACL1 |
| Family | Belongs to the histone deacetylase family. HD type 1 subfamily. |
| Sequence | MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYALHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGYDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEASGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSLHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKEVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITPSCRPDRNEPHRIQQILNYIKGNLKHVV Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Macaque | 699642 | HDAC8 | histone deacetylase 8 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 70315 | Hdac8 | histone deacetylase 8 | 10090 | MGI:1917565 | Inparanoid, OMA, EggNOG |
| Rat | 363481 | Hdac8 | histone deacetylase 8 | 10116 | RGD:1562895 | Inparanoid, OMA, EggNOG |
| Dog | 480957 | HDAC8 | histone deacetylase 8 | 9615 | VGNC:50631 | Inparanoid, OMA, EggNOG |
| Horse | HDAC8 | histone deacetylase 8 [Source:HGNC Symbol;Acc:HGNC:13315] | 9796 | OMA, EggNOG | ||
| Cow | 540666 | HDAC8 | histone deacetylase 8 | 9913 | Inparanoid, OMA, EggNOG | |
| Pig | 100625846 | HDAC8 | histone deacetylase 8 | 9823 | OMA, EggNOG | |
| Opossum | 100618462 | HDAC8 | histone deacetylase 8 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | HDAC8 | histone deacetylase 8 [Source:HGNC Symbol;Acc:HGNC:13315] | 9258 | OMA, EggNOG | ||
| Chicken | 422182 | HDAC8 | histone deacetylase 8 | 9031 | CGNC:3582 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100556612 | hdac8 | histone deacetylase 8 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100145561 | hdac8 | histone deacetylase 8 | 8364 | XB-GENE-5863426 | Inparanoid, OMA, EggNOG |
| Zebrafish | 406740 | hdac8 | histone deacetylase 8 | 7955 | ZDB-GENE-040426-2772 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / hydrolase / reductase / Histone deacetylase 8
protein / hydrolase / deacetylase / Histone deacetylase 8
protein / hydrolase / nucleic acid binding / Histone deacetylase 8
protein / hydrolase / reductase / Histone deacetylase 8
protein / hydrolase / deacetylase / Histone deacetylase 8
protein / hydrolase / nucleic acid binding / Histone deacetylase 8
DTO Classes
protein / Epigenetic regulator / Eraser / Histone deacetylase / HDAC class I / Histone deacetylase 8
protein / Epigenetic regulator / Eraser / Histone deacetylase / HDAC class I / Histone deacetylase 8
Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
|---|
Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
|---|---|---|---|
| Cornelia de Lange syndrome 5 | 1 | UniProt Disease | MONDO:0010471 |
| Wilson-Turner X-linked mental retardation syndrome | 0 | UniProt Disease | |
| Cornelia de Lange syndrome | 8 | Monarch | MONDO:0016033 |
| Wilson-Turner X-Linked Mental Retardation Syndrome | 2 | Monarch | MONDO:0010665 |
| Cornelia De Lange Syndrome 5 | 1 | Monarch | MONDO:0010471 |
| intraductal papillary-mucinous adenoma (IPMA) | 2987 | Expression Atlas | MONDO:0004381 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3325 | Expression Atlas | MONDO:0004286 |
| osteosarcoma | 7970 | Expression Atlas | MONDO:0009807 |
| cornelia de lange syndrome | 8 | eRAM | MONDO:0016033 |
| intellectual disability | 2078 | eRAM | MONDO:0001071 |