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PTK2

Description	Focal adhesion kinase 1

Gene and Protein Information

Gene ID	5747
Uniprot Accession IDs	B4E2N6 F5H4S4 J3QT16 Q14291 Q8IYN9 Q9UD85 FADK 1
Ensembl ID	ENSP00000341189
Symbol	FAK FAK1 FAK FADK FAK1 FRNK PPP1R71 p125FAK pp125FAK
Family	Belongs to the protein kinase superfamily. Tyr protein kinase family. FAK subfamily.
Sequence	MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	464422	PTK2	protein tyrosine kinase 2	9598	VGNC:813	OMA, EggNOG
Mouse	14083	Ptk2	PTK2 protein tyrosine kinase 2	10090	MGI:95481	Inparanoid, OMA, EggNOG
Rat	25614	Ptk2	protein tyrosine kinase 2	10116	RGD:3443	Inparanoid, OMA, EggNOG
Dog	475108	PTK2	protein tyrosine kinase 2	9615	VGNC:45158	Inparanoid, OMA, EggNOG
Horse	100058245	PTK2	protein tyrosine kinase 2	9796	VGNC:22002	Inparanoid, OMA, EggNOG
Cow	506270	PTK2	protein tyrosine kinase 2	9913	VGNC:33518	Inparanoid, OMA, EggNOG
Opossum	100027188	PTK2	protein tyrosine kinase 2	13616		Inparanoid, OMA, EggNOG
Platypus	100076789	PTK2	protein tyrosine kinase 2	9258		Inparanoid, OMA, EggNOG
Anole lizard	100554871	ptk2	protein tyrosine kinase 2	28377		Inparanoid, OMA
Xenopus	733890	ptk2	protein tyrosine kinase 2	8364	XB-GENE-952025	Inparanoid, OMA

DTO Classes
protein / Kinase / Protein kinase / TK group / FAK family / Focal adhesion kinase 1

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Name	Specifications	Species reactivity	species	Application	View Details

Name	Disease Type	Mondoid

Data Source	Name	Explore more targets	Explore in Source