PTK2

DescriptionFocal adhesion kinase 1

Gene and Protein Information

Gene ID5747
Uniprot Accession IDs B4E2N6 F5H4S4 J3QT16 Q14291 Q8IYN9 Q9UD85 FADK 1
Ensembl ID ENSP00000341189
Symbol FAK FAK1 FAK FADK FAK1 FRNK PPP1R71 p125FAK pp125FAK
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. FAK subfamily.
Sequence
MAAAYLDPNLNHTPNSSTKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGTSQSFIIRPQKEGERALPSIPKLANSEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNEGVKLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp464422PTK2protein tyrosine kinase 29598VGNC:813OMA, EggNOG
Mouse14083Ptk2PTK2 protein tyrosine kinase 210090MGI:95481Inparanoid, OMA, EggNOG
Rat25614Ptk2protein tyrosine kinase 210116RGD:3443Inparanoid, OMA, EggNOG
Dog475108PTK2protein tyrosine kinase 29615VGNC:45158Inparanoid, OMA, EggNOG
Horse100058245PTK2protein tyrosine kinase 29796VGNC:22002Inparanoid, OMA, EggNOG
Cow506270PTK2protein tyrosine kinase 29913VGNC:33518Inparanoid, OMA, EggNOG
Opossum100027188PTK2protein tyrosine kinase 213616Inparanoid, OMA, EggNOG
Platypus100076789PTK2protein tyrosine kinase 29258Inparanoid, OMA, EggNOG
Anole lizard100554871ptk2protein tyrosine kinase 228377Inparanoid, OMA
Xenopus733890ptk2protein tyrosine kinase 28364XB-GENE-952025Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    FAK family    /    Focal adhesion kinase 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source