GRK4

DescriptionG protein-coupled receptor kinase 4

Gene and Protein Information

Gene ID2868
Uniprot Accession IDs O00641 O00642 Q13293 Q13294 Q13295 Q14453 Q14725 Q15313 Q15314 Q15315 Q15316 Q17RH6 Q53EQ8
Ensembl ID ENSP00000381129
Symbol GPRK2L GPRK4 IT11 GPRK4 GRK4a GPRK2L
FamilyBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
Sequence
MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQPIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPEIPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQPVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLDIEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEMIESGCFKDINKSESEEALPLDLDKNIHTPVSRPNRGFFYRLFRRGGCLTMVPSEKEVEPKQC
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp461082GRK4G protein-coupled receptor kinase 49598VGNC:2985OMA, EggNOG
Mouse14772Grk4G protein-coupled receptor kinase 410090MGI:95801Inparanoid, OMA, EggNOG
Rat59077Grk4G protein-coupled receptor kinase 410116RGD:61858Inparanoid, OMA, EggNOG
Dog479075GRK4G protein-coupled receptor kinase 49615VGNC:41504Inparanoid, OMA
Horse100053624GRK4G protein-coupled receptor kinase 49796VGNC:18596Inparanoid, OMA
Cow512489GRK4G protein-coupled receptor kinase 49913VGNC:29655Inparanoid, OMA
Pig100519668GRK4G protein-coupled receptor kinase 49823Inparanoid, OMA, EggNOG
Opossum100021366GRK4G protein-coupled receptor kinase 413616Inparanoid, OMA
Chicken422879GRK4G protein-coupled receptor kinase 49031CGNC:51843Inparanoid, OMA
Xenopus448587grk4G protein-coupled receptor kinase 48364XB-GENE-480159Inparanoid, OMA
C. elegans181212grk-1G protein-coupled receptor kinase 16239Inparanoid, EggNOG
Fruitfly49045Gprk2G protein-coupled receptor kinase 27227FBgn0261988Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    G protein-coupled receptor kinase 4
protein    /    protein kinase    /    G protein-coupled receptor kinase 4
protein    /    transferase    /    G protein-coupled receptor kinase 4
protein    /    kinase    /    G protein-coupled receptor kinase 4
DTO Classes
protein    /    Kinase    /    Protein kinase    /    AGC group    /    GRK family    /    GRK subfamily    /    G protein-coupled receptor kinase 4

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source