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Protein or Target Summary

G protein-coupled receptor kinase 4

Gene ID2868
uniprotP32298
Gene NameGRK4
Ensernbl IDENSP00000381129
FamilyBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
Sequence
MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQPIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPEIPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQPVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLDIEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEMIESGCFKDINKSESEEALPLDLDKNIHTPVSRPNRGFFYRLFRRGGCLTMVPSEKEVEPKQC
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN2868GRK4G protein-coupled receptor kinase 4P32298
MOUSEGrk4G protein-coupled receptor kinase 4F7BEP0
MOUSEGrk4Uncharacterized proteinQ9D203
MOUSE14772Grk4G protein-coupled receptor kinase 4Q8BP13
MOUSE14772Grk4G protein-coupled receptor kinase 4O70291
RAT59077Grk4G protein-coupled receptor kinase 4P70507

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    G protein-coupled receptor kinase 4
protein    /    protein kinase    /    G protein-coupled receptor kinase 4
protein    /    transferase    /    G protein-coupled receptor kinase 4
protein    /    kinase    /    G protein-coupled receptor kinase 4
DTO Classes
protein    /    Kinase    /    Protein kinase    /    AGC group    /    GRK family    /    GRK subfamily    /    G protein-coupled receptor kinase 4

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source