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GRM5

Description	Metabotropic glutamate receptor 5

Gene and Protein Information

Gene ID	2915
Uniprot Accession IDs	Q6J164 mGluR5
Ensembl ID	ENSP00000306138
Symbol	GPRC1E MGLUR5 mGlu5 GPRC1E MGLUR5 PPP1R86
Family	Belongs to the G-protein coupled receptor 3 family.
Sequence	MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGICIAHSYKIYSNAGEQSFDKLLKKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNHRNPWFQEFWQHRFQCRLEGFPQENSKYNKTCNSSLTLKTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGYAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMDDDEVWSKKSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTSTVVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLRYKDRRLAQHKSEIECFTPKGSMGNGGRATMSSSNGKSVTWAQNEKSSRGQHLWQRLSIHINKKENPNQTAVIKPFPKSTESRGLGAGAGAGGSAGGVGATGGAGCAGAGPGGPESPDAGPKALYDVAEAEEHFPAPARPRSPSPISTLSHRAGSASRTDDDVPSLHSEPVARSSSSQGSLMEQISSVVTRFTANISELNSMMLSTAAPSPGVGAPLCSSYLIPKEIQLPTTMTTFAEIQPLPAIEVTGGAQPAAGAQAAGDAARESPAAGPEAAAAKPDLEELVALTPPSPFRDSVDSGSTTPNSPVSESALCIPSSPKYDTLIIRDYTQSSSSL Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	451472	GRM5	glutamate metabotropic receptor 5	9598	VGNC:11797	OMA, EggNOG
Macaque	705445	GRM5	glutamate metabotropic receptor 5	9544		OMA, EggNOG
Mouse	108071	Grm5	glutamate receptor, metabotropic 5	10090	MGI:1351342	Inparanoid, OMA
Rat	24418	Grm5	glutamate metabotropic receptor 5	10116	RGD:2746	Inparanoid, OMA, EggNOG
Dog	485146	GRM5	glutamate metabotropic receptor 5	9615	VGNC:41512	Inparanoid, OMA
Horse	100060364	GRM5	glutamate metabotropic receptor 5	9796	VGNC:18603	Inparanoid, OMA
Opossum		GRM5	glutamate metabotropic receptor 5 [Source:HGNC Symbol;Acc:HGNC:4597]	13616		Inparanoid, OMA
Platypus	100080549	GRM5	glutamate metabotropic receptor 5	9258		Inparanoid, OMA
Chicken	373933	GRM5	glutamate receptor, metabotropic 5	9031	CGNC:48964	Inparanoid, OMA
Anole lizard	100563209	grm5	glutamate metabotropic receptor 5	28377		Inparanoid, OMA
C. elegans	172914	mgl-2	Metabotropic GLutamate receptor family	6239		Inparanoid, OMA

Protein Classes

PANTHER Classes
protein / receptor / G-protein coupled receptor / Metabotropic glutamate receptor 5

DTO Classes
protein / G-protein coupled receptor / Class C metabotropic glutamate/pheromone / Metabotropic glutamate receptor / Metabotropic glutamate receptor 5

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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