GSDME

DescriptionGasdermin-E

Gene and Protein Information

Gene ID1687
Uniprot Accession IDs A4D156 B2RAX9 B3KT05 O14590 Q08AQ8 Q9UBV3
Ensembl ID ENSP00000339587
Symbol DFNA5 ICERE1 DFNA5 ICERE-1
FamilyBelongs to the gasdermin family.
Sequence
MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFWCWQRPKYQFLSLTLGDVLIEDQFPSPVVVESDFVKYEGKFANHVSGTLETALGKVKLNLGGSSRVESQSSFGTLRKQEVDLQQLIRDSAERTINLRNPVLQQVLEGRNEVLCVLTQKITTMQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIELYVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSVLKQATLLLERNFHPFAELPEPQQTALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAVLGELKPRQQQDLVAFLQLVGCSLQGGCPGPEDAGSKQLFMTAYFLVSALAEMPDSAAALLGTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKSSVKAVILKDSKVFPLLLCITLNGLCALGREHS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp463295GSDMEgasdermin E9598VGNC:9066OMA, EggNOG
Macaque703441GSDMEgasdermin E9544OMA, EggNOG
Mouse54722Gsdmegasdermin E10090MGI:1889850Inparanoid, OMA, EggNOG
Dog611223GSDMEgasdermin E9615VGNC:39911OMA, EggNOG
Horse100033992GSDMEgasdermin E9796VGNC:17143OMA, EggNOG
Cow616398GSDMEgasdermin E9913VGNC:28019OMA, EggNOG
Pig100522585GSDMEgasdermin E9823OMA, EggNOG
Opossum100014673GSDMEgasdermin E13616OMA, EggNOG
Chicken420623DFNA5DFNA5, deafness associated tumor suppressor9031CGNC:8357Inparanoid, OMA, EggNOG
Anole lizard100560065gsdmegasdermin E28377OMA, EggNOG
Xenopus100486029gsdmegasdermin E8364XB-GENE-983245OMA, EggNOG

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source