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KIT
| Description | Mast/stem cell growth factor receptor Kit |
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Gene and Protein Information
| Gene ID | 3815 |
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| Uniprot Accession IDs | B5A956 D5LXN2 D5M931 F5H8F8 Q6IQ28 Q99662 Q9UM99 SCFR |
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| Ensembl ID | ENSP00000288135 |
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| Symbol | SCFR PBT SCFR C-Kit CD117 MASTC |
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| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. |
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| Sequence | MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRVGDEIRLLCTDPGFVKWTFEILDETNENKQNEWITEKAEATNTGKYTCTNKHGLSNSIYVFVRDPAKLFLVDRSLYGKEDNDTLVRCPLTDPEVTNYSLKGCQGKPLPKDLRFIPDPKAGIMIKSVKRAYHRLCLHCSVDQEGKSVLSEKFILKVRPAFKAVPVVSVSKASYLLREGEEFTVTCTIKDVSSSVYSTWKRENSQTKLQEKYNSWHHGDFNYERQATLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPKPEHQQWIYMNRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKAYNDVGKTSAYFNFAFKGNNKEQIHPHTLFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNEYMDMKPGVSYVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPNRQKPVVDHSVRINSVGSTASSSQPLLVHDDV Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 461316 | KIT | KIT proto-oncogene receptor tyrosine kinase | 9598 | VGNC:6662 | OMA, EggNOG |
| Mouse | 16590 | Kit | KIT proto-oncogene receptor tyrosine kinase | 10090 | MGI:96677 | Inparanoid, OMA, EggNOG |
| Rat | 64030 | Kit | KIT proto-oncogene receptor tyrosine kinase | 10116 | RGD:620568 | Inparanoid, OMA, EggNOG |
| Dog | 403811 | KIT | KIT proto-oncogene receptor tyrosine kinase | 9615 | VGNC:42422 | Inparanoid, OMA, EggNOG |
| Horse | 100009704 | KIT | KIT proto-oncogene receptor tyrosine kinase | 9796 | VGNC:19433 | Inparanoid, OMA, EggNOG |
| Cow | 280832 | KIT | KIT proto-oncogene receptor tyrosine kinase | 9913 | VGNC:30618 | Inparanoid, OMA, EggNOG |
| Pig | 396810 | KIT | KIT proto-oncogene receptor tyrosine kinase | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100017501 | KIT | KIT proto-oncogene receptor tyrosine kinase | 13616 | | Inparanoid, OMA, EggNOG |
| Platypus | 100075317 | KIT | KIT proto-oncogene receptor tyrosine kinase | 9258 | | Inparanoid, OMA, EggNOG |
| Anole lizard | 100551543 | kit | KIT proto-oncogene receptor tyrosine kinase | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | | KIT | KIT proto-oncogene receptor tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:6342] | 8364 | | OMA, EggNOG |
| Zebrafish | 30256 | kita | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a | 7955 | ZDB-GENE-980526-464 | OMA, EggNOG |
| Zebrafish | 497629 | kitb | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b | 7955 | ZDB-GENE-050916-2 | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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