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INS

DescriptionInsulin

Gene and Protein Information

Gene ID3630
Uniprot Accession IDs P01308 Q5EEX2
Ensembl ID ENSP00000380432
Symbol IDDM ILPR IRDN IDDM1 IDDM2 MODY10
FamilyBelongs to the insulin family.
Sequence
MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp449570INSinsulin9598VGNC:1070Inparanoid, OMA, EggNOG
Macaque704534INSinsulin9544OMA, EggNOG
Mouse16334Ins2insulin II10090MGI:96573OMA, EggNOG
Mouse16333Ins1insulin I10090MGI:96572Inparanoid, OMA
Rat24506Ins2insulin 210116RGD:2916OMA, EggNOG
Rat24505Ins1insulin 110116RGD:2915Inparanoid, OMA
Dog483665INSinsulin9615Inparanoid, OMA
HorseINSinsulin [Source:HGNC Symbol;Acc:HGNC:6081]9796OMA, EggNOG
Cow280829INSinsulin9913Inparanoid, OMA, EggNOG
Chicken396145INSinsulin9031CGNC:4941Inparanoid, OMA, EggNOG
Anole lizard100565615insinsulin28377OMA, EggNOG
Xenopus100101718insinsulin8364XB-GENE-485905Inparanoid, OMA, EggNOG
Zebrafish30262inspreproinsulin7955ZDB-GENE-980526-110Inparanoid, OMA
Zebrafish566735insbpreproinsulin b7955ZDB-GENE-040113-2OMA, EggNOG

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details
Recombinant Insulin AntibodyHuman,Mouse,Rat
  • IHC
In stock
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Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      Bibliography

      1.Burren, C P CP, Wilson, E M EM, Hwa, V V, Oh, Y Y and Rosenfeld, R G RG. 1999-03 Binding properties and distribution of insulin-like growth factor binding protein-related protein 3 (IGFBP-rP3/NovH), an additional member of the IGFBP Superfamily. [PMID:10084601]
      2.Wang, J J, Takeuchi, T T, Yokota, H H and Izumi, T T. 1999-10-01 Novel rabphilin-3-like protein associates with insulin-containing granules in pancreatic beta cells. [PMID:10497219]
      3.Tang, L L, Whittingham, J L JL, Verma, C S CS, Caves, L S LS and Dodson, G G GG. 1999-09-14 Structural consequences of the B5 histidine --> tyrosine mutation in human insulin characterized by X-ray crystallography and conformational analysis. [PMID:10508408]
      4.Ma, H H, Ke, Y Y, Li, Q Q and Kapp, J A JA. 2000-01-01 Bovine and human insulin activate CD8+-autoreactive CTL expressing both type 1 and type 2 cytokines in C57BL/6 mice. [PMID:10604997]
      5.Riedel, H H and 5 more authors. 2000-01-06 PSM, a mediator of PDGF-BB-, IGF-I-, and insulin-stimulated mitogenesis. [PMID:10644978]
      6.Ban, N N and 16 more authors. 2000-07 Activating transcription factor-2 is a positive regulator in CaM kinase IV-induced human insulin gene expression. [PMID:10909971]
      7.Goodge, K A KA and Hutton, J C JC. 2000-08 Translational regulation of proinsulin biosynthesis and proinsulin conversion in the pancreatic beta-cell. [PMID:10966857]
      8.Battezzati, A A, Benedini, S S, Fattorini, A A, Piceni Sereni, L L and Luzi, L L. 2000-09 Effect of hypoglycemia on amino acid and protein metabolism in healthy humans. [PMID:10969839]
      9.Le Stunff, C C, Fallin, D D, Schork, N J NJ and Bougnères, P P. 2000-12 The insulin gene VNTR is associated with fasting insulin levels and development of juvenile obesity. [PMID:11101842]
      10.Comings, D E DE and 9 more authors. 2000-11 A multivariate analysis of 59 candidate genes in personality traits: the temperament and character inventory. [PMID:11140838]