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KCNH2
Description | Potassium voltage-gated channel subfamily H member 2 |
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Gene and Protein Information
Gene ID | 3757 |
Uniprot Accession IDs | A5H1P7 C4PFH9 D3DX04 O75418 O75680 Q708S9 Q9BT72 Q9BUT7 Q9H3P0 |
Ensembl ID | ENSP00000262186 |
Symbol | ERG ERG1 HERG ERG1 HERG LQT2 SQT1 ERG-1 H-ERG HERG1 Kv11.1 |
Family | Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily. |
Sequence | MPVRRGHVAPQNTFLDTIIRKFEGQSRKFIIANARVENCAVIYCNDGFCELCGYSRAEVMQRPCTCDFLHGPRTQRRAAAQIAQALLGAEERKVEIAFYRKDGSCFLCLVDVVPVKNEDGAVIMFILNFEVVMEKDMVGSPAHDTNHRGPPTSWLAPGRAKTFRLKLPALLALTARESSVRSGGAGGAGAPGAVVVDVDLTPAAPSSESLALDEVTAMDNHVAGLGPAEERRALVGPGSPPRSAPGQLPSPRAHSLNPDASGSSCSLARTRSRESCASVRRASSADDIEAMRAGVLPPPPRHASTGAMHPLRSGLLNSTSDSDLVRYRTISKIPQITLNFVDLKGDPFLASPTSDREIIAPKIKERTHNVTEKVTQVLSLGADVLPEYKLQAPRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAAFLLKETEEGPPATECGYACQPLAVVDLIVDIMFIVDILINFRTTYVNANEEVVSHPGRIAVHYFKGWFLIDMVAAIPFDLLIFGSGSEELIGLLKTARLLRLVRVARKLDRYSEYGAAVLFLLMCTFALIAHWLACIWYAIGNMEQPHMDSRIGWLHNLGDQIGKPYNSSGLGGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYPEFSDHFWSSLEITFNLRDTNMIPGSPGSTELEGGFSRQRKRKLSFRRRTDKDTEQPGEVSALGPGRAGAGPSSRGRPGGPWGESPSSGPSSPESSEDEGPGRSSSPLRLVPFSSPRPPGEPPGGEPLMEDCEKSSDTCNPLSGAFSGVSNIFSFWGDSRGRQYQELPRCPAPTPSLLNIPLSSPGRRPRGDVESRLDALQRQLNRLETRLSADMATVLQLLQRQMTLVPPAYSAVTTPGPGPTSTSPLLPVSPLPTLTLDSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS Show more |
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Homologous gene and protein info.
Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
Chimp | 463894 | KCNH2 | potassium voltage-gated channel subfamily H member 2 | 9598 | VGNC:8694 | OMA, EggNOG |
Macaque | 714174 | KCNH2 | potassium voltage-gated channel subfamily H member 2 | 9544 | | OMA, EggNOG |
Mouse | 16511 | Kcnh2 | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 10090 | MGI:1341722 | Inparanoid, OMA, EggNOG |
Rat | 117018 | Kcnh2 | potassium voltage-gated channel subfamily H member 2 | 10116 | RGD:621414 | Inparanoid, OMA, EggNOG |
Dog | 403761 | KCNH2 | potassium voltage-gated channel subfamily H member 2 | 9615 | VGNC:42248 | Inparanoid, OMA |
Opossum | 100017968 | KCNH2 | potassium voltage-gated channel subfamily H member 2 | 13616 | | Inparanoid, OMA |
Associated Recombinant Proteins
Associated Antibodies
Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
amiodaroneRETTclinIC
BLOCKER pIC50: 5.00
dofetilideRETTclinIC
BLOCKER pKi: 8.19
guanidineRETTclinIC
BLOCKER p: 0.00
sotalolRETTclinIC
BLOCKER pKi: 4.00
fampridineRETTclinIC
BLOCKER pIC50: 4.05
amifampridineRETTclinIC
BLOCKER p: 0.00
Associated Active Ligands
Associated Diseases
Name | Direct Associated Targets | Disease Type | Mondoid |
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