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INSRR

DescriptionInsulin receptor-related protein

Gene and Protein Information

Gene ID3645
Uniprot Accession IDs O60724 Q5VZS3 IRR
Ensembl ID ENSP00000357178
Symbol IRR IRR
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
Sequence
MAVPSLWPWGACLPVIFLSLGFGLDTVEVCPSLDIRSEVAELRQLENCSVVEGHLQILLMFTATGEDFRGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGTRLFLGYALVIFEMPHLRDVALPALGAVLRGAVRVEKNQELCHLSTIDWGLLQPAPGANHIVGNKLGEECADVCPGVLGAAGEPCAKTTFSGHTDYRCWTSSHCQRVCPCPHGMACTARGECCHTECLGGCSQPEDPRACVACRHLYFQGACLWACPPGTYQYESWRCVTAERCASLHSVPGRASTFGIHQGSCLAQCPSGFTRNSSSIFCHKCEGLCPKECKVGTKTIDSIQAAQDLVGCTHVEGSLILNLRQGYNLEPQLQHSLGLVETITGFLKIKHSFALVSLGFFKNLKLIRGDAMVDGNYTLYVLDNQNLQQLGSWVAAGLTIPVGKIYFAFNPRLCLEHIYRLEEVTGTRGRQNKAEINPRTNGDRAACQTRTLRFVSNVTEADRILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGTQSWNLLDVELPLSRTQEPGVTLASLKPWTQYAVFVRAITLTTEEDSPHQGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKPPTQRNGNLTYYLVLWQRLAEDGDLYLNDYCHRGLRLPTSNNDPRFDGEDGDPEAEMESDCCPCQHPPPGQVLPPLEAQEASFQKKFENFLHNAITIPISPWKVTSINKSPQRDSGRHRRAAGPLRLGGNSSDFEIQEDKVPRERAVLSGLRHFTEYRIDIHACNHAAHTVGCSAATFVFARTMPHREADGIPGKVAWEASSKNSVLLRWLEPPDPNGLILKYEIKYRRLGEEATVLCVSRLRYAKFGGVHLALLPPGNYSARVRATSLAGNGSWTDSVAFYILGPEEEDAGGLHVLLTATPVGLTLLIVLAALGFFYGKKRNRTLYASVNPEYFSASDMYVPDEWEVPREQISIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPALGEMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGGVLEELEGCPLQLQELMSRCWQPNPRLRPSFTHILDSIQEELRPSFRLLSFYYSPECRGARGSLPTTDAEPDSSPTPRDCSPQNGGPGH
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp457407INSRRinsulin receptor related receptor9598VGNC:9874OMA, EggNOG
Mouse23920Insrrinsulin receptor-related receptor10090MGI:1346037Inparanoid, OMA, EggNOG
Rat60663Insrrinsulin receptor-related receptor10116RGD:67399Inparanoid, OMA
Dog490405INSRRinsulin receptor related receptor9615VGNC:42044Inparanoid, OMA, EggNOG
Horse100058246INSRRinsulin receptor related receptor9796VGNC:19084Inparanoid, OMA, EggNOG
Cow787068INSRRinsulin receptor related receptor9913VGNC:30222Inparanoid, OMA, EggNOG
Pig100155702INSRRinsulin receptor related receptor9823Inparanoid, OMA, EggNOG
Opossum100023690INSRRinsulin receptor related receptor13616Inparanoid, OMA, EggNOG
Chicken100857811INSRRinsulin receptor related receptor9031CGNC:65247OMA, EggNOG
Anole lizard100556999insrrinsulin receptor related receptor28377Inparanoid, OMA, EggNOG
Xenopus100490498insrrinsulin receptor related receptor8364XB-GENE-483108Inparanoid, OMA
C. elegans175410daf-2Insulin-like receptor subunit beta6239Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    INSR family    /    Insulin receptor-related protein

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
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