GARS

DescriptionGlycine--tRNA ligase

Gene and Protein Information

Gene ID2617
Uniprot Accession IDs B3KQA2 B4DIA0 Q969Y1
Ensembl ID ENSP00000373918
Symbol HMN5 CMT2D DSMAV GlyRS SMAD1
FamilyBelongs to the class-II aminoacyl-tRNA synthetase family.
Sequence
MPSPRPVLLRGARAALLLLLPPRLLARPSLLLRRSLSAASCPPISLPAAASRSSMDGAGAEEVLAPLRLAVRQQGDLVRKLKEDKAPQVDVDKAVAELKARKRVLEAKELALQPKDDIVDRAKMEDTLKRRFFYDQAFAIYGGVSGLYDFGPVGCALKNNIIQTWRQHFIQEEQILEIDCTMLTPEPVLKTSGHVDKFADFMVKDVKNGECFRADHLLKAHLQKLMSDKKCSVEKKSEMESVLAQLDNYGQQELADLFVNYNVKSPITGNDLSPPVSFNLMFKTFIGPGGNMPGYLRPETAQGIFLNFKRLLEFNQGKLPFAAAQIGNSFRNEISPRSGLIRVREFTMAEIEHFVDPSEKDHPKFQNVADLHLYLYSAKAQVSGQSARKMRLGDAVEQGVINNTVLGYFIGRIYLYLTKVGISPDKLRFRQHMENEMAHYACDCWDAESKTSYGWIEIVGCADRSCYDLSCHARATKVPLVAEKPLKEPKTVNVVQFEPSKGAIGKAYKKDAKLVMEYLAICDECYITEMEMLLNEKGEFTIETEGKTFQLTKDMINVKRFQKTLYVEEVVPNVIEPSFGLGRIMYTVFEHTFHVREGDEQRTFFSFPAVVAPFKCSVLPLSQNQEFMPFVKELSEALTRHGVSHKVDDSSGSIGRRYARTDEIGVAFGVTIDFDTVNKTPHTATLRDRDSMRQIRAEISELPSIVQDLANGNITWADVEARYPLFEGQETGKKETIEE
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp463329GARSglycyl-tRNA synthetase9598VGNC:4365OMA, EggNOG
Macaque697526GARSglycyl-tRNA synthetase9544Inparanoid, OMA, EggNOG
Mouse353172Garsglycyl-tRNA synthetase10090MGI:2449057Inparanoid, OMA, EggNOG
Rat297113Garsglycyl-tRNA synthetase10116RGD:1307856Inparanoid, OMA, EggNOG
Dog100856659GARSglycyl-tRNA synthetase9615VGNC:41113Inparanoid, OMA, EggNOG
Horse100054985GARSglycyl-tRNA synthetase9796VGNC:18248Inparanoid, OMA, EggNOG
Cow408010GARSglycyl-tRNA synthetase9913VGNC:29254Inparanoid, OMA, EggNOG
Pig100512260GARSglycyl-tRNA synthetase9823OMA, EggNOG
PlatypusGARSglycyl-tRNA synthetase [Source:HGNC Symbol;Acc:HGNC:4162]9258OMA, EggNOG
Chicken428403GARSglycyl-tRNA synthetase9031CGNC:4244Inparanoid, OMA
Anole lizard100563154garsglycyl-tRNA synthetase28377Inparanoid, OMA, EggNOG
Xenopus493218garsglycyl-tRNA synthetase8364XB-GENE-963079Inparanoid, OMA, EggNOG
Zebrafish337230garsglycyl-tRNA synthetase7955ZDB-GENE-030131-9174Inparanoid, OMA, EggNOG
C. elegans175703gars-1Glycine--tRNA ligase6239Inparanoid, OMA, EggNOG
S.cerevisiae856196GRS2putative glycine--tRNA ligase4932S000006285Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    ligase    /    aminoacyl-tRNA synthetase    /    Glycine--tRNA ligase
DTO Classes
protein    /    Enzyme    /    Ligase    /    Aminoacyl-tRNA synthetase    /    Glycine--tRNA ligase

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source