ATIC

DescriptionBifunctional purine biosynthesis protein PURH

Gene and Protein Information

Gene ID471
Uniprot Accession IDs A8K202 E9PBU3 Q13856 Q53S28
Ensembl ID ENSP00000236959
Symbol PURH PURH AICAR AICARFT IMPCHASE HEL-S-70p
FamilyBelongs to the PurH family.
Sequence
MAPGQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp459925ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase9598VGNC:101OMA, EggNOG
Macaque694819ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase9544Inparanoid, OMA, EggNOG
Mouse108147Atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase10090MGI:1351352Inparanoid, OMA, EggNOG
Rat81643Atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase10116RGD:70879Inparanoid, OMA, EggNOG
Dog488513ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase9615VGNC:38229Inparanoid, OMA, EggNOG
Horse100054298ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase9796VGNC:15630Inparanoid, OMA, EggNOG
Cow506343ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase9913VGNC:26264Inparanoid, OMA, EggNOG
Pig100170854ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase9823Inparanoid, OMA, EggNOG
Opossum100012538ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase13616Inparanoid, OMA, EggNOG
Platypus100089876LOC100089876bifunctional purine biosynthesis protein PURH-like9258Inparanoid, EggNOG
Chicken396091ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase9031CGNC:2606Inparanoid, OMA, EggNOG
Anole lizard100559178atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase28377OMA, EggNOG
Xenopus448061atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase8364XB-GENE-998807Inparanoid, OMA, EggNOG
Zebrafish140622atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase7955ZDB-GENE-011212-4Inparanoid, OMA, EggNOG
S.cerevisiae850715ADE16bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase ADE164932S000004018Inparanoid, OMA
S.cerevisiae855149ADE17bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase ADE174932S000004727OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transferase    /    methyltransferase    /    Bifunctional purine biosynthesis protein PURH
protein    /    transferase    /    hydrolase    /    Bifunctional purine biosynthesis protein PURH
DTO Classes
protein    /    Enzyme    /    Transferase    /    Methyltransferase    /    Bifunctional purine biosynthesis protein PURH

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source