OPA1
| Description | Dynamin-like 120 kDa protein, mitochondrial |
|---|
Gene and Protein Information
| Gene ID | 4976 |
|---|---|
| Uniprot Accession IDs | D3DNW4 E5KLJ5 E5KLJ6 E5KLJ7 E5KLK1 E5KLK2 |
| Ensembl ID | ENSP00000354681 |
| Symbol | KIAA0567 NPG NTG MGM1 BERHS largeG MTDPS14 |
| Family | Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. |
| Sequence | MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQQFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFDQWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGSPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 471042 | OPA1 | OPA1, mitochondrial dynamin like GTPase | 9598 | VGNC:8843 | OMA, EggNOG |
| Macaque | 698540 | OPA1 | OPA1, mitochondrial dynamin like GTPase | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 74143 | Opa1 | OPA1, mitochondrial dynamin like GTPase | 10090 | MGI:1921393 | Inparanoid, OMA, EggNOG |
| Rat | 171116 | Opa1 | OPA1, mitochondrial dynamin like GTPase | 10116 | RGD:708423 | Inparanoid, OMA |
| Horse | 100059993 | OPA1 | OPA1, mitochondrial dynamin like GTPase | 9796 | VGNC:21035 | Inparanoid, OMA, EggNOG |
| Cow | 524142 | OPA1 | OPA1, mitochondrial dynamin like GTPase | 9913 | VGNC:32432 | Inparanoid, OMA, EggNOG |
| Pig | 100522705 | OPA1 | OPA1, mitochondrial dynamin like GTPase | 9823 | OMA, EggNOG | |
| Opossum | 100013661 | OPA1 | OPA1, mitochondrial dynamin like GTPase | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 424900 | OPA1 | OPA1, mitochondrial dynamin like GTPase | 9031 | CGNC:5403 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100557914 | opa1 | OPA1, mitochondrial dynamin like GTPase | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100145638 | opa1 | optic atrophy 1 (autosomal dominant) | 8364 | XB-GENE-989058 | Inparanoid, OMA, EggNOG |
| Zebrafish | 492332 | opa1 | optic atrophy 1 (autosomal dominant) | 7955 | ZDB-GENE-041114-7 | Inparanoid, OMA, EggNOG |
| C. elegans | 174476 | eat-3 | hypothetical protein | 6239 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / enzyme modulator / small GTPase / Dynamin-like 120 kDa protein, mitochondrial
protein / enzyme modulator / microtubule family cytoskeletal protein / Dynamin-like 120 kDa protein, mitochondrial
protein / enzyme modulator / hydrolase / Dynamin-like 120 kDa protein, mitochondrial
protein / enzyme modulator / small GTPase / Dynamin-like 120 kDa protein, mitochondrial
protein / enzyme modulator / microtubule family cytoskeletal protein / Dynamin-like 120 kDa protein, mitochondrial
protein / enzyme modulator / hydrolase / Dynamin-like 120 kDa protein, mitochondrial
DTO Classes
protein / Enzyme modulator / G-protein / Small GTPase / Dynamin-like 120 kDa protein, mitochondrial
protein / Enzyme modulator / G-protein / Small GTPase / Dynamin-like 120 kDa protein, mitochondrial
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
|---|
Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
|---|
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
|---|