PSEN2
| Description | Presenilin-2 |
|---|
Gene and Protein Information
| Gene ID | 5664 |
|---|---|
| Uniprot Accession IDs | A8K8D4 B1AP21 Q96P32 PS-2 |
| Ensembl ID | ENSP00000355747 |
| Symbol | AD4 PS2 PSNL2 STM2 AD4 PS2 AD3L STM2 CMD1V |
| Family | Belongs to the peptidase A22A family. |
| Sequence | MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGPEDGENTAQWRSQENEEDGEEDPDRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLTGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 457790 | PSEN2 | presenilin 2 | 9598 | VGNC:1474 | OMA, EggNOG |
| Macaque | 698770 | PSEN2 | presenilin 2 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 19165 | Psen2 | presenilin 2 | 10090 | MGI:109284 | Inparanoid, OMA, EggNOG |
| Rat | 81751 | Psen2 | presenilin 2 | 10116 | RGD:621060 | Inparanoid, OMA, EggNOG |
| Dog | 490382 | PSEN2 | presenilin 2 | 9615 | VGNC:45086 | Inparanoid, OMA, EggNOG |
| Horse | 100054506 | PSEN2 | presenilin 2 | 9796 | VGNC:21930 | Inparanoid, OMA, EggNOG |
| Cow | 282010 | PSEN2 | presenilin 2 | 9913 | VGNC:33435 | Inparanoid, OMA, EggNOG |
| Pig | 780410 | PSEN2 | presenilin 2 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100026453 | PSEN2 | presenilin 2 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | PSEN2 | presenilin 2 [Source:HGNC Symbol;Acc:HGNC:9509] | 9258 | OMA, EggNOG | ||
| Chicken | 374188 | PSEN2 | presenilin 2 | 9031 | CGNC:6904 | Inparanoid, OMA |
| Anole lizard | 100567182 | psen2 | presenilin 2 | 28377 | Inparanoid, OMA | |
| Xenopus | 549935 | psen2 | presenilin 2 | 8364 | XB-GENE-854877 | Inparanoid, OMA |
| Zebrafish | 58026 | psen2 | presenilin 2 | 7955 | ZDB-GENE-000330-9 | Inparanoid, OMA |
| C. elegans | 180441 | sel-12 | Presenilin sel-12 | 6239 | Inparanoid, OMA |
Protein Classes
PANTHER Classes
protein / signaling molecule / membrane-bound signaling molecule / Presenilin-2
protein / signaling molecule / aspartic protease / Presenilin-2
protein / signaling molecule / protease / Presenilin-2
protein / signaling molecule / calcium-binding protein / Presenilin-2
protein / signaling molecule / hydrolase / Presenilin-2
protein / signaling molecule / membrane-bound signaling molecule / Presenilin-2
protein / signaling molecule / aspartic protease / Presenilin-2
protein / signaling molecule / protease / Presenilin-2
protein / signaling molecule / calcium-binding protein / Presenilin-2
protein / signaling molecule / hydrolase / Presenilin-2
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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