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HSPD1

Description60 kDa heat shock protein, mitochondrial

Gene and Protein Information

Gene ID3329
Uniprot Accession IDs P10809 B2R5M6 B7Z712 Q38L19 Q9UCR6
Ensembl ID ENSP00000373620
Symbol HSP60 HLD4 CPN60 GROEL HSP60 HSP65 SPG13 HSP-60 HuCHA60
FamilyBelongs to the chaperonin (HSP60) family.
Sequence
MLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque698024HSPD1heat shock protein family D (Hsp60) member 19544Inparanoid, OMA
Mouse15510Hspd1heat shock protein 1 (chaperonin)10090MGI:96242Inparanoid, OMA, EggNOG
Rat63868Hspd1heat shock protein family D member 110116RGD:621314Inparanoid, OMA, EggNOG
Dog478854HSPD1heat shock protein family D (Hsp60) member 19615OMA, EggNOG
Horse100055147HSPD1heat shock protein family D (Hsp60) member 19796VGNC:51461Inparanoid, OMA, EggNOG
Cow511913HSPD1heat shock protein family D (Hsp60) member 19913VGNC:49070Inparanoid, OMA, EggNOG
Pig492279HSPD1heat shock protein family D (Hsp60) member 19823Inparanoid, OMA, EggNOG
Opossum100022262HSPD1heat shock protein family D (Hsp60) member 113616Inparanoid, OMA, EggNOG
Chicken424059HSPD1heat shock protein family D (Hsp60) member 19031CGNC:6130Inparanoid, OMA, EggNOG
Anole lizard100558963hspd1heat shock protein family D (Hsp60) member 128377Inparanoid, OMA, EggNOG
Xenopus100124945hspd1heat shock protein family D (Hsp60) member 18364XB-GENE-980059Inparanoid, OMA, EggNOG
Zebrafish282676hspd1heat shock 60 protein 17955ZDB-GENE-021206-1Inparanoid, OMA, EggNOG
C. elegans175316hsp-60Chaperonin homolog Hsp-60, mitochondrial6239Inparanoid, OMA, EggNOG
Fruitfly33796Hsp60CHeat shock protein 60C7227FBgn0031728Inparanoid, OMA
S.cerevisiae850963HSP60chaperone ATPase HSP604932S000004249Inparanoid, OMA, EggNOG

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details
Recombinant Human Hsp60 ProteinE. coliN-His
In stock
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Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Bibliography

      1.Samali, A A, Cai, J J, Zhivotovsky, B B, Jones, D P DP and Orrenius, S S. 1999-04-15 Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells. [PMID:10205158]
      2.Xanthoudakis, S S and 9 more authors. 1999-04-15 Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis. [PMID:10205159]
      3.Tabibzadeh, S S and Broome, J J. 1999 Heat shock proteins in human endometrium throughout the menstrual cycle. [PMID:10231001]
      4.Giraldo, P P, Neuer, A A, Ribeiro-Filho, A A, Linhares, I I and Witkin, S S SS. 1999 Detection of the human 70-kD and 60-kD heat shock proteins in the vagina: relation to microbial flora, vaginal pH, and method of contraception. [PMID:10231004]
      5.Latif, N N, Taylor, P M PM, Khan, M A MA, Yacoub, M H MH and Dunn, M J MJ. 1999-04 The expression of heat shock protein 60 in patients with dilated cardiomyopathy. [PMID:10326659]
      6.Komatsuda, A A and 6 more authors. 1999-06 Overexpression of the human 72 kDa heat shock protein in renal tubular cells confers resistance against oxidative injury and cisplatin toxicity. [PMID:10382997]
      7.Ziegert, M M and 5 more authors. 1999 Heat shock proteins and heat shock protein-antibody complexes in placental tissues. [PMID:10449265]
      8.Pockley, A G AG, Bulmer, J J, Hanks, B M BM and Wright, B H BH. 1999-03 Identification of human heat shock protein 60 (Hsp60) and anti-Hsp60 antibodies in the peripheral circulation of normal individuals. [PMID:10467106]
      9.Speth, C C and 7 more authors. 1999-06 A 60 kD heat-shock protein-like molecule interacts with the HIV transmembrane glycoprotein gp41. [PMID:10499815]
      10.Schäfer, C C and Williams, J A JA. 2000 Stress kinases and heat shock proteins in the pancreas: possible roles in normal function and disease. [PMID:10632533]