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Protein or Target Summary

BDNF/NT-3 growth factors receptor

Gene ID4915
uniprotQ16620
Gene NameNTRK2
Ensernbl IDENSP00000277120
FamilyBelongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
Sequence
MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEPNSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHINFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNESSKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHMNETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHHWCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYTLIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPSTDVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASPLHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVLKRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHIVKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQEVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN4915NTRK2BDNF/NT-3 growth factors receptorQ16620
MOUSENtrk2Neurotrophic tyrosine kinase receptor, type2, splicing variant T3 betaB5BQV4
MOUSENtrk2Neurotrophic tyrosine receptor kinase type 2W8R8Q6
MOUSENtrk2BDNF/NT-3 growth factors receptorA0A286YCB7
MOUSE18212Ntrk2BDNF/NT-3 growth factors receptorA0A286YDA3
MOUSENtrk2Neurotrophic tyrosine receptor kinase type 2S5N1F5
MOUSE18212Ntrk2Uncharacterized proteinQ3UHE3
MOUSENtrk2Neurotrophic tyrosine kinase receptor, type2, splicing variant T3 alphaB5BQV3
MOUSENtrk2BDNF/NT-3 growth factors receptorA0A286YCV8
MOUSENtrk2BDNF/NT-3 growth factors receptorA0A286YDA0
MOUSE18212Ntrk2BDNF/NT-3 growth factors receptorP15209
RAT25054Ntrk2Tyrosine-protein kinase receptorA0A0G2K5X6
RATNtrk2Neurotrophic tyrosine kinase receptor type 2Q7TSD7
RAT25054Ntrk2BDNF/NT-3 growth factors receptorQ63604

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TK group    /    TRK family    /    Bdnf/nt-3 growth factors receptor

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
      Source: DataSourcesLicenses.xlsx
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