PREP

Description	Prolyl endopeptidase

Gene and Protein Information

Gene ID	5550
Uniprot Accession IDs	Q8N6D4 PE
Ensembl ID	ENSP00000358106
Symbol	PEP PE PEP
Family	Belongs to the peptidase S9A family.
Sequence	MLSLQYPDVYRDETAVQDYHGHKICDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNSYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESSGIAGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRQSPNYRVINIDFRDPEESKWKVLVPEHEKDVLEWIACVRSNFLVLCYLHDVKNILQLHDLTTGALLKTFPLDVGSIVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGILAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVAACANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEWLVKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQSNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNVDWIP Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	462903	PREP	prolyl endopeptidase	9598	VGNC:11186	OMA, EggNOG
Macaque	696633	PREP	prolyl endopeptidase	9544		Inparanoid, OMA, EggNOG
Mouse	19072	Prep	prolyl endopeptidase	10090	MGI:1270863	Inparanoid, OMA, EggNOG
Rat	83471	Prep	prolyl endopeptidase	10116	RGD:620841	Inparanoid, OMA
Dog	481945	PREP	prolyl endopeptidase	9615	VGNC:44960	Inparanoid, OMA, EggNOG
Horse	100071926	PREP	prolyl endopeptidase	9796	VGNC:21827	Inparanoid, OMA, EggNOG
Cow	286818	PREP	prolyl endopeptidase	9913	VGNC:33310	Inparanoid, OMA, EggNOG
Pig	445540	PREP	prolyl endopeptidase	9823		Inparanoid, OMA, EggNOG
Opossum	100021189	PREP	prolyl endopeptidase	13616		Inparanoid, OMA, EggNOG
Platypus		PREP	prolyl endopeptidase [Source:HGNC Symbol;Acc:HGNC:9358]	9258		OMA, EggNOG
Chicken	421785	PREP	prolyl endopeptidase	9031	CGNC:11476	Inparanoid, OMA, EggNOG
Anole lizard	100562705	prep	prolyl endopeptidase	28377		Inparanoid, OMA, EggNOG
Zebrafish	553791	prep	prolyl endopeptidase	7955	ZDB-GENE-050522-14	Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    serine protease    /    Prolyl endopeptidase
protein    /    protease    /    Prolyl endopeptidase
protein    /    hydrolase    /    Prolyl endopeptidase

DTO Classes
protein / Enzyme / Protease / Serine protease / Prolyl endopeptidase

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source