NKX2-1

DescriptionHomeobox protein Nkx-2.1

Gene and Protein Information

Gene ID7080
Uniprot Accession IDs D3DSA3 O14954 O14955 Q7KZF6 Q9BRJ8
Ensembl ID ENSP00000346879
Symbol NKX2A TITF1 TTF1 BCH BHC NK-2 TEBP TTF1 NKX2A NMTC1 T/EBP TITF1 TTF-1 NKX2.1
FamilyBelongs to the NK-2 homeobox family.
Sequence
MSMSPKHTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQGQAAPPTAAMQQHAVGHHGAVTAAYHMTAAGVPQLSHSAVGGYCNGNLGNMSELPPYQDTMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGDVSKNMAPLPSAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPCQAGAPAPGAASLQGHAQQQAQHQAQAAQAAAAAISVGSGGAGLGAHPGHQPGSAGQSPDLAHHAASPAALQGQVSSLSHLNSSGSDYGTMSCSTLLYGRTW
Show more
Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp452867NKX2-1NK2 homeobox 19598VGNC:3364OMA, EggNOG
Mouse21869Nkx2-1NK2 homeobox 110090MGI:108067Inparanoid, OMA, EggNOG
Rat25628Nkx2-1NK2 homeobox 110116RGD:3866Inparanoid, OMA, EggNOG
Horse100146136NKX2-1NK2 homeobox 19796VGNC:20753Inparanoid, OMA, EggNOG
Cow613713NKX2-1NK2 homeobox 19913VGNC:49980Inparanoid, OMA, EggNOG
Pig100154384NKX2-1NK2 homeobox 19823OMA, EggNOG
Opossum100011516NKX2-1NK2 homeobox 113616Inparanoid, EggNOG
Anole lizard100557406nkx2-1NK2 homeobox 128377Inparanoid, OMA, EggNOG
Xenopus100135015nkx2-1NK2 homeobox 18364XB-GENE-485985Inparanoid, OMA
C. elegans179877ceh-24Homeobox protein ceh-246239Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    DNA binding protein    /    Homeobox protein Nkx-2.1
protein    /    nucleic acid binding    /    homeodomain transcription factor    /    Homeobox protein Nkx-2.1
DTO Classes
protein    /    Transcription factor    /    Helix-turn-helix transcription factor    /    Homeodomain transcription factor    /    Homeobox protein Nkx-2.1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source