GRIN2A

DescriptionGlutamate receptor ionotropic, NMDA 2A

Gene and Protein Information

Gene ID2903
Uniprot Accession IDs O00669 Q17RZ6 GluN2A
Ensembl ID ENSP00000379818
Symbol NMDAR2A LKS EPND FESD NR2A GluN2A NMDAR2A
FamilyBelongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2A/GRIN2A subfamily.
Sequence
MGRVGYWTLLVLPALLVWRGPAPSAAAEKGPPALNIAVMLGHSHDVTERELRTLWGPEQAAGLPLDVNVVALLMNRTDPKSLITHVCDLMSGARIHGLVFGDDTDQEAVAQMLDFISSHTFVPILGIHGGASMIMADKDPTSTFFQFGASIQQQATVMLKIMQDYDWHVFSLVTTIFPGYREFISFVKTTVDNSFVGWDMQNVITLDTSFEDAKTQVQLKKIHSSVILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTELIPKEFPSGLISVSYDDWDYSLEARVRDGIGILTTAASSMLEKFSYIPEAKASCYGQMERPEVPMHTLHPFMVNVTWDGKDLSFTEEGYQVHPRLVVIVLNKDREWEKVGKWENHTLSLRHAVWPRYKSFSDCEPDDNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNVKKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKVNNVWNGMIGEVVYQRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRSNGTVSPSAFLEPFSASVWVMMFVMLLIVSAIAVFVFEYFSPVGYNRNLAKGKAPHGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDKKFQRPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTKFNQKGVEDALVSLKTGKLDAFIYDAAVLNYKAGRDEGCKLVTIGSGYIFATTGYGIALQKGSPWKRQIDLALLQFVGDGEMEELETLWLTGICHNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIWEHLFYWKLRFCFTGVCSDRPGLLFSISRGIYSCIHGVHIEEKKKSPDFNLTGSQSNMLKLLRSAKNISSMSNMNSSRMDSPKRAADFIQRGSLIMDMVSDKGNLMYSDNRSFQGKESIFGDNMNELQTFVANRQKDNLNNYVFQGQHPLTLNESNPNTVEVAVSTESKANSRPRQLWKKSVDSIRQDSLSQNPVSQRDEATAENRTHSLKSPRYLPEEMAHSDISETSNRATCHREPDNSKNHKTKDNFKRSVASKYPKDCSEVERTYLKTKSSSPRDKIYTIDGEKEPGFHLDPPQFVENVTLPENVDFPDPYQDPSENFRKGDSTLPMNRNPLHNEEGLSNNDQYKLYSKHFTLKDKGSPHSETSERYRQNSTHCRSCLSNMPTYSGHFTMRSPFKCDACLRMGNLYDIDEDQMLQETGNPATGEQVYQQDWAQNNALQLQKNKLRISRQHSYDNIVDKPRELDLSRPSRSISLKDRERLLEGNFYGSLFSVPSSKLSGKKSSLFPQGLEDSKRSKSLLPDHTSDNPFLHSHRDDQRLVIGRCPSDPYKHSLPSQAVNDSYLRSSLRSTASYCSRDSRGHNDVYISEHVMPYAANKNNMYSTPRVLNSCSNRRVYKKMPSIESDV
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp454396GRIN2Aglutamate ionotropic receptor NMDA type subunit 2A9598VGNC:8981Inparanoid, OMA, EggNOG
Macaque100429880GRIN2Aglutamate ionotropic receptor NMDA type subunit 2A9544OMA, EggNOG
Mouse14811Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)10090MGI:95820Inparanoid, OMA, EggNOG
Rat24409Grin2aglutamate ionotropic receptor NMDA type subunit 2A10116RGD:2737Inparanoid, OMA, EggNOG
Dog490012GRIN2Aglutamate ionotropic receptor NMDA type subunit 2A9615VGNC:41492Inparanoid, OMA
Cow524212GRIN2Aglutamate ionotropic receptor NMDA type subunit 2A9913VGNC:29646Inparanoid, OMA
Opossum100018255GRIN2Aglutamate ionotropic receptor NMDA type subunit 2A13616Inparanoid, OMA
Platypus100074436GRIN2Aglutamate ionotropic receptor NMDA type subunit 2A9258Inparanoid, OMA
Chicken427678GRIN2Aglutamate ionotropic receptor NMDA type subunit 2A9031CGNC:5502Inparanoid, OMA
Zebrafish563297grin2aaglutamate receptor, ionotropic, N-methyl D-aspartate 2A, a7955ZDB-GENE-070424-129Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Ion channel    /    Glutamate-gated ion channel (GIC) Family of Neurotransmitter Receptors    /    NR2A/GRIN2A subfamily    /    Glutamate receptor ionotropic, NMDA 2A

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source