GRIN2B

DescriptionGlutamate receptor ionotropic, NMDA 2B

Gene and Protein Information

Gene ID2904
Uniprot Accession IDs Q12919 Q13220 Q13225 Q14CU4 Q9UM56 GluN2B
Ensembl ID ENSP00000477455
Symbol NMDAR2B NR3 MRD6 NR2B hNR3 EIEE27 GluN2B NMDAR2B
FamilyBelongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B subfamily.
Sequence
MKPRAECCSPKFWLVLAVLAVSGSRARSQKSPPSIGIAVILVGTSDEVAIKDAHEKDDFHHLSVVPRVELVAMNETDPKSIITRICDLMSDRKIQGVVFADDTDQEAIAQILDFISAQTLTPILGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQNQLKKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDTVPAEFPTGLISVSYDEWDYGLPARVRDGIAIITTAASDMLSEHSFIPEPKSSCYNTHEKRIYQSNMLNRYLINVTFEGRNLSFSEDGYQMHPKLVIILLNKERKWERVGKWKDKSLQMKYYVWPRMCPETEEQEDDHLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRIVTENKTDEEPGYIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKKINGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGREPGGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNNYAEMHAYMGKFNQRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHNEKNEVMSSQLDIDNMAGVFYMLGAAMALSLITFICEHLFYWQFRHCFMGVCSGKPGMVFSISRGIYSCIHGVAIEERQSVMNSPTATMNNTHSNILRLLRTAKNMANLSGVNGSPQSALDFIRRESSVYDISEHRRSFTHSDCKSYNNPPCEENLFSDYISEVERTFGNLQLKDSNVYQDHYHHHHRPHSIGSASSIDGLYDCDNPPFTTQSRSISKKPLDIGLPSSKHSQLSDLYGKFSFKSDRYSGHDDLIRSDVSDISTHTVTYGNIEGNAAKRRKQQYKDSLKKRPASAKSRREFDEIELAYRRRPPRSPDHKRYFRDKEGLRDFYLDQFRTKENSPHWEHVDLTDIYKERSDDFKRDSVSGGGPCTNRSHIKHGTGDKHGVVSGVPAPWEKNLTNVEWEDRSGGNFCRSCPSKLHNYSTTVTGQNSGRQACIRCEACKKAGNLYDISEDNSLQELDQPAAPVAVTSNASTTKYPQSPTNSKAQKKNRNKLRRQHSYDTFVDLQKEEAALAPRSVSLKDKGRFMDGSPYAHMFEMSAGESTFANNKSSVPTAGHHHHNNPGGGYMLSKSLYPDRVTQNPFIPTFGDDQCLLHGSKSYFFRQPTVAGASKARPDFRALVTNKPVVSALHGAVPARFQKDICIGNQSNPCVPNNKNPRAFNGSSNGHVYEKLSSIESDV
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque698571GRIN2Bglutamate ionotropic receptor NMDA type subunit 2B9544Inparanoid, OMA
Mouse14812Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)10090MGI:95821Inparanoid, OMA
Rat24410Grin2bglutamate ionotropic receptor NMDA type subunit 2B10116RGD:2738Inparanoid, OMA
Dog494009GRIN2Bglutamate ionotropic receptor NMDA type subunit 2B9615VGNC:41493Inparanoid, OMA
Horse100063746GRIN2Bglutamate ionotropic receptor NMDA type subunit 2B9796VGNC:18589Inparanoid, OMA
Cow537804GRIN2Bglutamate ionotropic receptor NMDA type subunit 2B9913VGNC:29647Inparanoid, OMA
Pig100626022GRIN2Bglutamate ionotropic receptor NMDA type subunit 2B9823Inparanoid, OMA
Opossum100017355GRIN2Bglutamate ionotropic receptor NMDA type subunit 2B13616Inparanoid, OMA
Chicken417965GRIN2Bglutamate ionotropic receptor NMDA type subunit 2B9031CGNC:8954Inparanoid, OMA
Zebrafish559976grin2bbglutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b7955ZDB-GENE-061207-27Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Ion channel    /    Glutamate-gated ion channel (GIC) Family of Neurotransmitter Receptors    /    NR2B/GRIN2B subfamily    /    Glutamate receptor ionotropic, nmda 2b

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

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