Protein or Target Summary

DNA ligase 1

Gene ID3978
uniprotP18858
Gene NameLIG1
Ensernbl IDENSP00000263274
FamilyBelongs to the ATP-dependent DNA ligase family.
Sequence
MQRSIMSFFHPKKEGKAKKPEKEASNSSRETEPPPKAALKEWNGVVSESDSPVKRPGRKAARVLGSEGEEEDEALSPAKGQKPALDCSQVSPPRPATSPENNASLSDTSPMDSSPSGIPKRRTARKQLPKRTIQEVLEEQSEDEDREAKRKKEEEEEETPKESLTEAEVATEKEGEDGDQPTTPPKPLKTSKAETPTESVSEPEVATKQELQEEEEQTKPPRRAPKTLSSFFTPRKPAVKKEVKEEEPGAPGKEGAAEGPLDPSGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSDPEDTY
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Gene and Protein Information

SpeciesGene IDGene SymbolGene NameUniprot
HUMAN3978LIG1DNA ligase 1P18858
MOUSE16881Lig1DNA ligase 1P37913
MOUSELig1DNA ligase 1D3YUW4
MOUSELig1DNA ligase 1E9PV36
MOUSELig1Uncharacterized proteinQ8BPJ2
MOUSELig1DNA ligaseQ8R055
MOUSELig1DNA ligase 1V9GWZ4
MOUSE16881Lig1DNA ligaseQ3TSU8
MOUSE16881Lig1DNA ligaseQ3U4X8
RATLig1DNA ligase 1Q9JHY8
RAT81513Lig1DNA ligaseQ566D8

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    DNA binding protein    /    DNA ligase 1
protein    /    nucleic acid binding    /    DNA ligase    /    DNA ligase 1
protein    /    nucleic acid binding    /    ligase    /    DNA ligase 1
DTO Classes
protein    /    Enzyme    /    Ligase    /    DNA ligase    /    DNA ligase 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source