SMPD2

DescriptionSphingomyelin phosphodiesterase 2

Gene and Protein Information

Gene ID6610
Uniprot Accession IDs Q5TED1 Q9BWR3
Ensembl ID ENSP00000258052
Symbol ISC1 NSMASE NSMASE1
FamilyBelongs to the neutral sphingomyelinase family.
Sequence
MKPNFSLRLRIFNLNCWGIPYLSKHRADRMRRLGDFLNQESFDLALLEEVWSEQDFQYLRQKLSPTYPAAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLLVLHLSGMVLNAYVTHLHAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDLGCCLLKEWTGLHDAYLETRDFKGSEEGNTMVPKNCYVSQQELKPFPFGVRIDYVLYKAVSGFYISCKSFETTTGFDPHRGTPLSDHEALMATLFVRHSPPQQNPSSTHGPAERSPLMCVLKEAWTELGLGMAQARWWATFASYVIGLGLLLLALLCVLAAGGGAGEAAILLWTPSVGLVLWAGAFYLFHVQEVNGLYRAQAELQHVLGRAREAQDLGPEPQPALLLGQQEGDRTKEQ
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp462928SMPD2sphingomyelin phosphodiesterase 29598VGNC:7929OMA, EggNOG
Mouse20598Smpd2sphingomyelin phosphodiesterase 2, neutral10090MGI:1278330Inparanoid, OMA, EggNOG
Rat83537Smpd2sphingomyelin phosphodiesterase 210116RGD:619753Inparanoid, OMA, EggNOG
Dog100856377SMPD2sphingomyelin phosphodiesterase 29615VGNC:46570Inparanoid, OMA, EggNOG
Horse100066652SMPD2sphingomyelin phosphodiesterase 29796VGNC:23354Inparanoid, OMA, EggNOG
Cow509018SMPD2sphingomyelin phosphodiesterase 29913VGNC:35030Inparanoid, OMA, EggNOG
Pig100152155SMPD2sphingomyelin phosphodiesterase 29823OMA, EggNOG
Opossum100029088SMPD2sphingomyelin phosphodiesterase 213616Inparanoid, OMA, EggNOG
Anole lizard100552784smpd2sphingomyelin phosphodiesterase 228377Inparanoid, OMA, EggNOG
Xenopus100145256smpd2sphingomyelin phosphodiesterase 28364XB-GENE-982632Inparanoid, OMA, EggNOG
Zebrafish567548smpd2asphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase)7955ZDB-GENE-051014-1OMA, EggNOG
Fruitfly38396CG12034CG12034 gene product from transcript CG12034-RA7227FBgn0035421Inparanoid, OMA, EggNOG
S.cerevisiae856739ISC1inositol phosphosphingolipid phospholipase4932S000000821Inparanoid, EggNOG

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source