Protein or Target Summary

Presenilin-1

Gene ID	5663
uniprot	P49768
Gene Name	PSEN1
Ensernbl ID	ENSP00000326366
Family	Belongs to the peptidase A22A family.
Sequence	MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI Show more

Gene and Protein Information

Species	Gene ID	Gene Symbol	Gene Name	Uniprot
HUMAN	5663	PSEN1	Presenilin-1	P49768
MOUSE		Psen1	Presenilin	Q3TDW2
MOUSE	19164	Psen1	Presenilin	Q3UYK2
MOUSE	19164	Psen1	Presenilin-1	P49769
RAT	29192	Psen1	Presenilin-1	P97887

Protein Classes

PANTHER Classes
protein    /    signaling molecule    /    membrane-bound signaling molecule    /    Presenilin-1
protein    /    signaling molecule    /    aspartic protease    /    Presenilin-1
protein    /    signaling molecule    /    protease    /    Presenilin-1
protein    /    signaling molecule    /    calcium-binding protein    /    Presenilin-1
protein    /    signaling molecule    /    hydrolase    /    Presenilin-1

DTO Classes
protein / Enzyme / Protease / Aspartic protease / Presenilin-1

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

Source: DataSourcesLicenses.xlsx