PSEN1
| Description | Presenilin-1 |
|---|
Gene and Protein Information
| Gene ID | 5663 |
|---|---|
| Uniprot Accession IDs | B2R6D3 O95465 Q14762 Q15719 Q15720 Q96P33 Q9UIF0 PS-1 |
| Ensembl ID | ENSP00000326366 |
| Symbol | AD3 PS1 PSNL1 AD3 FAD PS1 PS-1 S182 ACNINV3 |
| Family | Belongs to the peptidase A22A family. |
| Sequence | MTELPAPLSYFQNAQMSEDNHLSNTVRSQNDNRERQEHNDRRSLGHPEPLSNGRPQGNSRQVVEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTEDTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIISSLLLLFFFSFIYLGEVFKTYNVAVDYITVALLIWNFGVVGMISIHWKGPLRLQQAYLIMISALMALVFIKYLPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAEGDPEAQRRVSKNSKYNAESTERESQDTVAENDDGGFSEEWEAQRDSHLGPHRSTPESRAAVQELSSSILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPALPISITFGLVFYFATDYLVQPFMDQLAFHQFYI Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 739740 | PSEN1 | presenilin 1 | 9598 | VGNC:3326 | OMA, EggNOG |
| Macaque | 696274 | PSEN1 | presenilin 1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 19164 | Psen1 | presenilin 1 | 10090 | MGI:1202717 | Inparanoid, OMA, EggNOG |
| Rat | 29192 | Psen1 | presenilin 1 | 10116 | RGD:3425 | Inparanoid, OMA, EggNOG |
| Dog | 403408 | PSEN1 | presenilin 1 | 9615 | VGNC:45085 | Inparanoid, OMA, EggNOG |
| Horse | PSEN1 | presenilin 1 [Source:HGNC Symbol;Acc:HGNC:9508] | 9796 | OMA, EggNOG | ||
| Cow | 282705 | PSEN1 | presenilin 1 | 9913 | VGNC:33434 | Inparanoid, OMA, EggNOG |
| Pig | 780411 | PSEN1 | presenilin 1 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100019628 | PSEN1 | presenilin 1 | 13616 | Inparanoid, EggNOG | |
| Platypus | 100091250 | PSEN1 | presenilin 1 | 9258 | OMA, EggNOG | |
| Chicken | 373977 | PSEN1 | presenilin 1 | 9031 | CGNC:7083 | Inparanoid, OMA |
| Anole lizard | 100553615 | psen1 | presenilin 1 | 28377 | Inparanoid, OMA | |
| Xenopus | 394924 | psen1 | presenilin 1 | 8364 | XB-GENE-481916 | Inparanoid, OMA, EggNOG |
| Zebrafish | 30221 | psen1 | presenilin 1 | 7955 | ZDB-GENE-991119-4 | Inparanoid, OMA |
| C. elegans | 180441 | sel-12 | Presenilin sel-12 | 6239 | OMA, EggNOG | |
| Fruitfly | 40260 | Psn | Presenilin | 7227 | FBgn0019947 | Inparanoid, EggNOG |
Protein Classes
PANTHER Classes
protein / signaling molecule / membrane-bound signaling molecule / Presenilin-1
protein / signaling molecule / aspartic protease / Presenilin-1
protein / signaling molecule / protease / Presenilin-1
protein / signaling molecule / calcium-binding protein / Presenilin-1
protein / signaling molecule / hydrolase / Presenilin-1
protein / signaling molecule / membrane-bound signaling molecule / Presenilin-1
protein / signaling molecule / aspartic protease / Presenilin-1
protein / signaling molecule / protease / Presenilin-1
protein / signaling molecule / calcium-binding protein / Presenilin-1
protein / signaling molecule / hydrolase / Presenilin-1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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