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IL6ST

DescriptionInterleukin-6 receptor subunit beta

Gene and Protein Information

Gene ID3572
Uniprot Accession IDs A0N0L4 Q5FC04 Q9UQ41 IL-6 receptor subunit beta
Ensembl ID ENSP00000370698
Symbol CD130 GP130 CDW130 IL-6RB
FamilyBelongs to the type I cytokine receptor family. Type 2 subfamily.
Sequence
MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEGMPKSYLPQTVRQGGYMPQ
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp461866IL6STinterleukin 6 signal transducer9598VGNC:13514OMA, EggNOG
Macaque574127IL6STinterleukin 6 signal transducer9544Inparanoid, OMA, EggNOG
Mouse16195Il6stinterleukin 6 signal transducer10090MGI:96560Inparanoid, OMA, EggNOG
Rat25205Il6stinterleukin 6 signal transducer10116RGD:2903Inparanoid, OMA, EggNOG
Dog403545IL6STinterleukin 6 signal transducer9615VGNC:41994Inparanoid, OMA, EggNOG
Horse100051700IL6STinterleukin 6 signal transducer9796VGNC:19036Inparanoid, OMA, EggNOG
Cow522155IL6STinterleukin 6 signal transducer9913VGNC:30168Inparanoid, OMA, EggNOG
Pig100037294IL6STinterleukin 6 signal transducer9823Inparanoid, OMA, EggNOG
Opossum100017284IL6STinterleukin 6 signal transducer13616Inparanoid, OMA, EggNOG
Platypus100073530IL6STinterleukin 6 signal transducer9258Inparanoid, OMA, EggNOG
Chicken395684IL6STinterleukin 6 signal transducer9031CGNC:10911Inparanoid, OMA, EggNOG
Anole lizard100562134il6stinterleukin 6 signal transducer28377Inparanoid, OMA, EggNOG
Xenopus100489642il6stinterleukin 6 signal transducer8364XB-GENE-855663Inparanoid, OMA, EggNOG
Zebrafish100006778il6stinterleukin 6 signal transducer7955ZDB-GENE-080104-6Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    signaling molecule    /    defense/immunity protein    /    Interleukin-6 receptor subunit beta
protein    /    signaling molecule    /    cytokine    /    Interleukin-6 receptor subunit beta
DTO Classes
protein    /    Signaling    /    Cytokine    /    Interleukin-6 receptor subunit beta

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelAvailabilityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityApplicationAvailabilityView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDirect Associated TargetsDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source
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