IL6ST

Description	Interleukin-6 receptor subunit beta

Gene and Protein Information

Gene ID	3572
Uniprot Accession IDs	A0N0L4 Q5FC04 Q9UQ41 IL-6 receptor subunit beta
Ensembl ID	ENSP00000370698
Symbol	CD130 GP130 CDW130 IL-6RB
Family	Belongs to the type I cytokine receptor family. Type 2 subfamily.
Sequence	MLTLQTWLVQALFIFLTTESTGELLDPCGYISPESPVVQLHSNFTAVCVLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTIINRTASSVTFTDIASLNIQLTCNILTFGQLEQNVYGITIISGLPPEKPKNLSCIVNEGKKMRCEWDGGRETHLETNFTLKSEWATHKFADCKAKRDTPTSCTVDYSTVYFVNIEVWVEAENALGKVTSDHINFDPVYKVKPNPPHNLSVINSEELSSILKLTWTNPSIKSVIILKYNIQYRTKDASTWSQIPPEDTASTRSSFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSEEASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQLVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTVNATKLTVNLTNDRYLATLTVRNLVGKSDAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEWTTPRESVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYLRGNLAESKCYLITVTPVYADGPGSPESIKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISSSDENESSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDHVDGGDGILPRQQYFKQNCSQHESSPDISHFERSKQVSSVNEEDFVRLKQQISDHISQSCGSGQMKMFQEVSAADAFGPGTEGQVERFETVGMEAATDEGMPKSYLPQTVRQGGYMPQ Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	461866	IL6ST	interleukin 6 signal transducer	9598	VGNC:13514	OMA, EggNOG
Macaque	574127	IL6ST	interleukin 6 signal transducer	9544		Inparanoid, OMA, EggNOG
Mouse	16195	Il6st	interleukin 6 signal transducer	10090	MGI:96560	Inparanoid, OMA, EggNOG
Rat	25205	Il6st	interleukin 6 signal transducer	10116	RGD:2903	Inparanoid, OMA, EggNOG
Dog	403545	IL6ST	interleukin 6 signal transducer	9615	VGNC:41994	Inparanoid, OMA, EggNOG
Horse	100051700	IL6ST	interleukin 6 signal transducer	9796	VGNC:19036	Inparanoid, OMA, EggNOG
Cow	522155	IL6ST	interleukin 6 signal transducer	9913	VGNC:30168	Inparanoid, OMA, EggNOG
Pig	100037294	IL6ST	interleukin 6 signal transducer	9823		Inparanoid, OMA, EggNOG
Opossum	100017284	IL6ST	interleukin 6 signal transducer	13616		Inparanoid, OMA, EggNOG
Platypus	100073530	IL6ST	interleukin 6 signal transducer	9258		Inparanoid, OMA, EggNOG
Chicken	395684	IL6ST	interleukin 6 signal transducer	9031	CGNC:10911	Inparanoid, OMA, EggNOG
Anole lizard	100562134	il6st	interleukin 6 signal transducer	28377		Inparanoid, OMA, EggNOG
Xenopus	100489642	il6st	interleukin 6 signal transducer	8364	XB-GENE-855663	Inparanoid, OMA, EggNOG
Zebrafish	100006778	il6st	interleukin 6 signal transducer	7955	ZDB-GENE-080104-6	Inparanoid, OMA

Protein Classes

PANTHER Classes
protein / signaling molecule / defense/immunity protein / Interleukin-6 receptor subunit beta
protein / signaling molecule / cytokine / Interleukin-6 receptor subunit beta

DTO Classes
protein / Signaling / Cytokine / Interleukin-6 receptor subunit beta

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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