JavaScript seems to be disabled in your browser. For the best experience on our site, be sure to turn on Javascript in your browser.

྾

JAK2

Description	Tyrosine-protein kinase JAK2

Gene and Protein Information

Gene ID	3717
Uniprot Accession IDs	O14636 O75297
Ensembl ID	ENSP00000371067
Symbol	JTK10 THCYT3
Family	Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
Sequence	MGMACLTMTEMEGTSTSSIYQNGDISGNANSMKQIDPVLQVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPRWYCSGSNRAYRHGISRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLGMAVLDMMRIAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNLKLKYLINLETLQSAFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSRGKHKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	464979	JAK2	Janus kinase 2	9598	VGNC:4770	OMA, EggNOG
Macaque	694184	JAK2	Janus kinase 2	9544		Inparanoid, OMA, EggNOG
Mouse	16452	Jak2	Janus kinase 2	10090	MGI:96629	Inparanoid, OMA, EggNOG
Rat	24514	Jak2	Janus kinase 2	10116	RGD:2939	Inparanoid, OMA
Dog	484185	JAK2	Janus kinase 2	9615	VGNC:42176	Inparanoid, OMA
Horse	100051487	JAK2	Janus kinase 2	9796	VGNC:19213	Inparanoid, OMA
Cow	525246	JAK2	Janus kinase 2	9913	VGNC:30365	Inparanoid, OMA
Pig	397201	JAK2	Janus kinase 2	9823		Inparanoid, OMA
Opossum	100017930	JAK2	Janus kinase 2	13616		Inparanoid, OMA
Platypus	100074305	JAK2	Janus kinase 2	9258		Inparanoid, OMA
Chicken	374199	JAK2	Janus kinase 2	9031	CGNC:11173	Inparanoid, OMA
Anole lizard	100552375	jak2	Janus kinase 2	28377		Inparanoid, OMA
Xenopus	100036599	jak2	Janus kinase 2 (a protein tyrosine kinase)	8364	XB-GENE-483712	Inparanoid, OMA
Zebrafish	30298	jak2b	Janus kinase 2b	7955	ZDB-GENE-980526-123	Inparanoid, OMA

DTO Classes
protein / Kinase / Protein kinase / TK group / JAKA family / Tyrosine-protein kinase jak2

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Name	Specifications	Species reactivity	species	Application	View Details

Name	Disease Type	Mondoid

Data Source	Name	Explore more targets	Explore in Source