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JAK2
Description | Tyrosine-protein kinase JAK2 |
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Gene and Protein Information
Gene ID | 3717 |
Uniprot Accession IDs | O14636 O75297 |
Ensembl ID | ENSP00000371067 |
Symbol | JTK10 THCYT3 |
Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily. |
Sequence | MGMACLTMTEMEGTSTSSIYQNGDISGNANSMKQIDPVLQVYLYHSLGKSEADYLTFPSGEYVAEEICIAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPRWYCSGSNRAYRHGISRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLGMAVLDMMRIAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNLKLKYLINLETLQSAFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSRGKHKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSNESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPAVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGDENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG Show more |
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Homologous gene and protein info.
Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
Chimp | 464979 | JAK2 | Janus kinase 2 | 9598 | VGNC:4770 | OMA, EggNOG |
Macaque | 694184 | JAK2 | Janus kinase 2 | 9544 | | Inparanoid, OMA, EggNOG |
Mouse | 16452 | Jak2 | Janus kinase 2 | 10090 | MGI:96629 | Inparanoid, OMA, EggNOG |
Rat | 24514 | Jak2 | Janus kinase 2 | 10116 | RGD:2939 | Inparanoid, OMA |
Dog | 484185 | JAK2 | Janus kinase 2 | 9615 | VGNC:42176 | Inparanoid, OMA |
Horse | 100051487 | JAK2 | Janus kinase 2 | 9796 | VGNC:19213 | Inparanoid, OMA |
Cow | 525246 | JAK2 | Janus kinase 2 | 9913 | VGNC:30365 | Inparanoid, OMA |
Pig | 397201 | JAK2 | Janus kinase 2 | 9823 | | Inparanoid, OMA |
Opossum | 100017930 | JAK2 | Janus kinase 2 | 13616 | | Inparanoid, OMA |
Platypus | 100074305 | JAK2 | Janus kinase 2 | 9258 | | Inparanoid, OMA |
Chicken | 374199 | JAK2 | Janus kinase 2 | 9031 | CGNC:11173 | Inparanoid, OMA |
Anole lizard | 100552375 | jak2 | Janus kinase 2 | 28377 | | Inparanoid, OMA |
Xenopus | 100036599 | jak2 | Janus kinase 2 (a protein tyrosine kinase) | 8364 | XB-GENE-483712 | Inparanoid, OMA |
Zebrafish | 30298 | jak2b | Janus kinase 2b | 7955 | ZDB-GENE-980526-123 | Inparanoid, OMA |
Associated Recombinant Proteins
Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
Data Source | Name | Explore more targets | Explore in Source |
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