KDM5B

Description	Lysine-specific demethylase 5B

Gene and Protein Information

Gene ID	10765
Uniprot Accession IDs	O95811 Q15752 Q9Y3Q5
Ensembl ID	ENSP00000356234
Symbol	JARID1B PLU1 RBBP2H1 CT31 PLU1 PUT1 MRT65 PLU-1 JARID1B PPP1R98 RBP2-H1 RBBP2H1A
Family	Belongs to the JARID1 histone demethylase family.
Sequence	MEAATTLHPGPRPALPLGGPGPLGEFLPPPECPVFEPSWEEFADPFAFIHKIRPIAEQTGICKVRPPPDWQPPFACDVDKLHFTPRIQRLNELEAQTRVKLNFLDQIAKYWELQGSTLKIPHVERKILDLFQLNKLVAEEGGFAVVCKDRKWTKIATKMGFAPGKAVGSHIRGHYERILNPYNLFLSGDSLRCLQKPNLTTDTKDKEYKPHDIPQRQSVQPSETCPPARRAKRMRAEAMNIKIEPEETTEARTHNLRRRMGCPTPKCENEKEMKSSIKQEPIERKDYIVENEKEKPKSRSKKATNAVDLYVCLLCGSGNDEDRLLLCDGCDDSYHTFCLIPPLHDVPKGDWRCPKCLAQECSKPQEAFGFEQAARDYTLRTFGEMADAFKSDYFNMPVHMVPTELVEKEFWRLVSTIEEDVTVEYGADIASKEFGSGFPVRDGKIKLSPEEEEYLDSGWNLNNMPVMEQSVLAHITADICGMKLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGVPGYAAEQLENVMKKLAPELFVSQPDLLHQLVTIMNPNTLMTHEVPVYRTNQCAGEFVITFPRAYHSGFNQGFNFAEAVNFCTVDWLPLGRQCVEHYRLLHRYCVFSHDEMICKMASKADVLDVVVASTVQKDMAIMIEDEKALRETVRKLGVIDSERMDFELLPDDERQCVKCKTTCFMSAISCSCKPGLLVCLHHVKELCSCPPYKYKLRYRYTLDDLYPMMNALKLRAESYNEWALNVNEALEAKINKKKSLVSFKALIEESEMKKFPDNDLLRHLRLVTQDAEKCASVAQQLLNGKRQTRYRSGGGKSQNQLTVNELRQFVTQLYALPCVLSQTPLLKDLLNRVEDFQQHSQKLLSEETPSAAELQDLLDVSFEFDVELPQLAEMRIRLEQARWLEEVQQACLDPSSLTLDDMRRLIDLGVGLAPYSAVEKAMARLQELLTVSEHWDDKAKSLLKARPRHSLNSLATAVKEIEEIPAYLPNGAALKDSVQRARDWLQDVEGLQAGGRVPVLDTLIELVTRGRSIPVHLNSLPRLETLVAEVQAWKECAVNTFLTENSPYSLLEVLCPRCDIGLLGLKRKQRKLKEPLPNGKKKSTKLESLSDLERALTESKETASAMATLGEARLREMEALQSLRLANEGKLLSPLQDVDIKICLCQKAPAAPMIQCELCRDAFHTSCVAVPSISQGLRIWLCPHCRRSEKPPLEKILPLLASLQRIRVRLPEGDALRYMIERTVNWQHRAQQLLSSGNLKFVQDRVGSGLLYSRWQASAGQVSDTNKVSQPPGTTSFSLPDDWDNRTSYLHSPFSTGRSCIPLHGVSPEVNELLMEAQLLQVSLPEIQELYQTLLAKPSPAQQTDRSSPVRPSSEKNDCCRGKRDGINSLERKLKRRLEREGLSSERWERVKKMRTPKKKKIKLSHPKDMNNFKLERERSYELVRSAETHSLPSDTSYSEQEDSEDEDAICPAVSCLQPEGDEVDWVQCDGSCNQWFHQVCVGVSPEMAEKEDYICVRCTVKDAPSRK Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	457630	KDM5B	lysine demethylase 5B	9598	VGNC:8062	Inparanoid, OMA, EggNOG
Macaque	706437	KDM5B	lysine demethylase 5B	9544		Inparanoid, OMA, EggNOG
Mouse	75605	Kdm5b	lysine (K)-specific demethylase 5B	10090	MGI:1922855	Inparanoid, OMA, EggNOG
Rat	304809	Kdm5b	lysine demethylase 5B	10116	RGD:1565602	Inparanoid, OMA
Dog	479999	KDM5B	lysine demethylase 5B	9615	VGNC:42328	Inparanoid, OMA, EggNOG
Horse	100064707	KDM5B	lysine demethylase 5B	9796	VGNC:19340	Inparanoid, OMA, EggNOG
Cow	540633	KDM5B	lysine demethylase 5B	9913	VGNC:30531	Inparanoid, OMA, EggNOG
Pig	102163404	KDM5B	lysine demethylase 5B	9823		OMA, EggNOG
Opossum	100011885	KDM5B	lysine demethylase 5B	13616		Inparanoid, OMA, EggNOG
Platypus	100077577	KDM5B	lysine demethylase 5B	9258		Inparanoid, OMA, EggNOG
Anole lizard	100562356	kdm5b	lysine demethylase 5B	28377		Inparanoid, OMA, EggNOG
Xenopus	100488170	kdm5b	lysine demethylase 5B	8364	XB-GENE-856240	Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein / transcription factor / zinc finger transcription factor / Lysine-specific demethylase 5B

DTO Classes
protein / Epigenetic regulator / Eraser / Lysine demethylase / Jumonji domain-containing / Lysine-specific demethylase 5B

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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