PRKCA

DescriptionProtein kinase C alpha type

Gene and Protein Information

Gene ID5578
Uniprot Accession IDs B5BU22 Q15137 Q32M72 Q96RE4 PKC-A
Ensembl ID ENSP00000408695
Symbol PKCA PRKACA AAG6 PKCA PRKACA PKCI+/- PKCalpha PKC-alpha
FamilyBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Sequence
MADVFPGNDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVADEKLHVTVRDAKNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNMELRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQSIMEHNVSYPKSLSKEAVSVCKGLMTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp454832PRKCAprotein kinase C alpha9598VGNC:12611OMA, EggNOG
Macaque718412PRKCAprotein kinase C alpha9544Inparanoid, OMA, EggNOG
Mouse18750Prkcaprotein kinase C, alpha10090MGI:97595Inparanoid, OMA, EggNOG
Rat24680Prkcaprotein kinase C, alpha10116RGD:3395Inparanoid, OMA, EggNOG
Dog490904PRKCAprotein kinase C alpha9615VGNC:44978Inparanoid, OMA, EggNOG
Horse100063318PRKCAprotein kinase C alpha9796VGNC:21843Inparanoid, OMA, EggNOG
Cow282001PRKCAprotein kinase C alpha9913VGNC:33327Inparanoid, OMA, EggNOG
Opossum100024674PRKCAprotein kinase C alpha13616Inparanoid, OMA, EggNOG
Platypus100079107PRKCAprotein kinase C alpha9258Inparanoid, OMA, EggNOG
Zebrafish497384prkcaprotein kinase C, alpha7955ZDB-GENE-050208-100Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    calcium-binding protein    /    non-receptor serine/threonine protein kinase    /    Protein kinase c alpha type
protein    /    calcium-binding protein    /    transfer/carrier protein    /    Protein kinase c alpha type
protein    /    calcium-binding protein    /    protein kinase    /    Protein kinase c alpha type
protein    /    calcium-binding protein    /    calmodulin    /    Protein kinase c alpha type
protein    /    calcium-binding protein    /    annexin    /    Protein kinase c alpha type
protein    /    calcium-binding protein    /    transferase    /    Protein kinase c alpha type
protein    /    calcium-binding protein    /    kinase    /    Protein kinase c alpha type
DTO Classes
protein    /    Kinase    /    Protein kinase    /    AGC group    /    PKC family    /    PKC alpha subfamily    /    Protein kinase c alpha type

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source