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Targets(Human)
CIT

CIT

Description	Citron Rho-interacting kinase

Gene and Protein Information

Gene ID	11113
Uniprot Accession IDs	Q2M5E1 Q6XUH8 Q86UQ9 Q9UPZ7 CRIK
Ensembl ID	ENSP00000376306
Symbol	CRIK KIAA0949 STK21 CITK CRIK STK21 MCPH17
Family	Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Sequence	MLKFKYGARNPLDAGAAEPIASRASRLNLFFQGKPPFMTQQQMSPLSREGILDALFVLFEECSQPALMKIKHVSNFVRKYSDTIAELQELQPSAKDFEVRSLVGCGHFAEVQVVREKATGDIYAMKVMKKKALLAQEQVSFFEEERNILSRSTSPWIPQLQYAFQDKNHLYLVMEYQPGGDLLSLLNRYEDQLDENLIQFYLAELILAVHSVHLMGYVHRDIKPENILVDRTGHIKLVDFGSAAKMNSNKMVNAKLPIGTPDYMAPEVLTVMNGDGKGTYGLDCDWWSVGVIAYEMIYGRSPFAEGTSARTFNNIMNFQRFLKFPDDPKVSSDFLDLIQSLLCGQKERLKFEGLCCHPFFSKIDWNNIRNSPPPFVPTLKSDDDTSNFDEPEKNSWVSSSPCQLSPSGFSGEELPFVGFSYSKALGILGRSESVVSGLDSPAKTSSMEKKLLIKSKELQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKASETQRSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQEIKEQEYQAQVEEMRLMMNQLEEDLVSARRRSDLYESELRESRLAAEEFKRKATECQHKLLKAKDQGKPEVGEYAKLEKINAEQQLKIQELQEKLEKAVKASTEATELLQNIRQAKERAERELEKLQNREDSSEGIRKKLVEAEELEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQLRSEVDHLRREITEREMQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQEALDRADLLKTERSDLEYQLENIQVLYSHEKVKMEGTISQQTKLIDFLQAKMDQPAKKKKGLFSRRKEDPALPTQVPLQYNELKLALEKEKARCAELEEALQKTRIELRSAREEAAHRKATDHPHPSTPATARQQIAMSAIVRSPEHQPSAMSLLAPPSSRRKESSTPEEFSRRLKERMHHNIPHRFNVGLNMRATKCAVCLDTVHFGRQASKCLECQVMCHPKCSTCLPATCGLPAEYATHFTEAFCRDKMNSPGLQTKEPSSSLHLEGWMKVPRNNKRGQQGWDRKYIVLEGSKVLIYDNEAREAGQRPVEEFELCLPDGDVSIHGAVGASELANTAKADVPYILKMESHPHTTCWPGRTLYLLAPSFPDKQRWVTALESVVAGGRVSREKAEADAKLLGNSLLKLEGDDRLDMNCTLPFSDQVVLVGTEEGLYALNVLKNSLTHVPGIGAVFQIYIIKDLEKLLMIAGEERALCLVDVKKVKQSLAQSHLPAQPDISPNIFEAVKGCHLFGAGKIENGLCICAAMPSKVVILRYNENLSKYCIRKEIETSEPCSCIHFTNYSILIGTNKFYEIDMKQYTLEEFLDKNDHSLAPAVFAASSNSFPVSIVQVNSAGQREEYLLCFHEFGVFVDSYGRRSRTDDLKWSRLPLAFAYREPYLFVTHFNSLEVIEIQARSSAGTPARAYLDIPNPRYLGPAISSGAIYLASSYQDKLRVICCKGNLVKESGTEHHRGPSTSRSSPNKRGPPTYNEHITKRVASSPAPPEGPSHPREPSTPHRYREGRTELRRDKSPGRPLEREKSPGRMLSTRRERSPGRLFEDSSRGRLPAGAVRTPLSQVNKVWDQSSV Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	108449892	CIT	citron rho-interacting serine/threonine kinase	9598		Inparanoid, OMA, EggNOG
Macaque	695846	CIT	citron rho-interacting serine/threonine kinase	9544		OMA, EggNOG
Mouse	12704	Cit	citron	10090	MGI:105313	Inparanoid, OMA, EggNOG
Rat	83620	Cit	citron rho-interacting serine/threonine kinase	10116	RGD:70878	Inparanoid, OMA, EggNOG
Dog	100683247	CIT	citron rho-interacting serine/threonine kinase	9615	VGNC:39282	Inparanoid, OMA, EggNOG
Horse	100050621	CIT	citron rho-interacting serine/threonine kinase	9796	VGNC:49361	Inparanoid, OMA, EggNOG
Cow	786852	CIT	citron rho-interacting serine/threonine kinase	9913	VGNC:27375	Inparanoid, OMA, EggNOG
Pig	100153706	CIT	citron rho-interacting serine/threonine kinase	9823		Inparanoid, OMA
Opossum	100014244	CIT	citron rho-interacting serine/threonine kinase	13616		Inparanoid, OMA, EggNOG
Chicken	416984	CIT	citron rho-interacting serine/threonine kinase	9031	CGNC:5556	Inparanoid, OMA, EggNOG
Anole lizard	100553665	cit	citron rho-interacting serine/threonine kinase	28377		Inparanoid, OMA, EggNOG
Xenopus	100145758	cit	citron rho-interacting serine/threonine kinase	8364	XB-GENE-981097	Inparanoid, OMA, EggNOG
Fruitfly	39429	sti	sticky	7227	FBgn0002466	Inparanoid, EggNOG

Protein Classes

DTO Classes
protein / Kinase / Protein kinase / AGC group / DMPK family / Citron rho-interacting kinase

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Associated Antibodies

Name	Specifications	Species reactivity	species	Application	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Disease Type	Mondoid

Pathway

Data Source	Name	Explore more targets	Explore in Source

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