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RPS6KA4

Description	Ribosomal protein S6 kinase alpha-4

Gene and Protein Information

Gene ID	8986
Uniprot Accession IDs	A8K7Z8 O75585 Q53ES8 S6K-alpha-4
Ensembl ID	ENSP00000333896
Symbol	MSK2 MSK2 RSK-B S6K-alpha-4
Family	Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
Sequence	MGDEDDDESCAVELRITEANLTGHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVARSAMMQDSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSATASRRGSPAPANPGRAPVASKGAPRRANGPLPPS Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	451715	RPS6KA4	ribosomal protein S6 kinase A4	9598	VGNC:8305	OMA, EggNOG
Macaque	717574	RPS6KA4	ribosomal protein S6 kinase A4	9544		Inparanoid, OMA, EggNOG
Mouse	56613	Rps6ka4	ribosomal protein S6 kinase, polypeptide 4	10090	MGI:1930076	Inparanoid, OMA, EggNOG
Rat	361715	Rps6ka4	ribosomal protein S6 kinase A4	10116	RGD:1307277	Inparanoid, OMA, EggNOG
Dog	612105	RPS6KA4	ribosomal protein S6 kinase A4	9615	VGNC:45741	Inparanoid, OMA
Horse	100050279	RPS6KA4	ribosomal protein S6 kinase A4	9796	VGNC:22560	Inparanoid, OMA, EggNOG
Cow	523746	RPS6KA4	ribosomal protein S6 kinase A4	9913	VGNC:34143	Inparanoid, OMA, EggNOG
Pig	100626270	RPS6KA4	ribosomal protein S6 kinase A4	9823		Inparanoid, OMA
Anole lizard	100552228	rps6ka4	ribosomal protein S6 kinase A4	28377		Inparanoid, OMA
Xenopus	100486973	rps6ka4	ribosomal protein S6 kinase, 90kDa, polypeptide 4	8364	XB-GENE-5759516	Inparanoid, OMA, EggNOG
C. elegans	172581	rskn-2	Putative ribosomal protein S6 kinase alpha-2	6239		Inparanoid, OMA
Fruitfly	39241	JIL-1	JIL-1 kinase	7227	FBgn0020412	Inparanoid, EggNOG

DTO Classes
protein / Kinase / Protein kinase / AGC group / RSK family / MSK subfamily / Ribosomal protein s6 kinase alpha-4

Name	Specification and purity	Expression system	Protein label	Activity	View Details

Name	Specifications	Species reactivity	species	Application	View Details

Name	Disease Type	Mondoid

Data Source	Name	Explore more targets	Explore in Source