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RPS6KA4
| Description | Ribosomal protein S6 kinase alpha-4 |
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Gene and Protein Information
| Gene ID | 8986 |
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| Uniprot Accession IDs | A8K7Z8 O75585 Q53ES8 S6K-alpha-4 |
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| Ensembl ID | ENSP00000333896 |
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| Symbol | MSK2 MSK2 RSK-B S6K-alpha-4 |
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| Family | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. |
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| Sequence | MGDEDDDESCAVELRITEANLTGHEEKVSVENFELLKVLGTGAYGKVFLVRKAGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRSKTGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPPRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVRNHPFFQGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPPGSPPPGDPRIFQGYSFVAPSILFDHNNAVMTDGLEAPGAGDRPGRAAVARSAMMQDSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEANTQREVAALRLCQSHPNVVNLHEVHHDQLHTYLVLELLRGGELLEHIRKKRHFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPGVPMQTPCFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRGSSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSATASRRGSPAPANPGRAPVASKGAPRRANGPLPPS Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 451715 | RPS6KA4 | ribosomal protein S6 kinase A4 | 9598 | VGNC:8305 | OMA, EggNOG |
| Macaque | 717574 | RPS6KA4 | ribosomal protein S6 kinase A4 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 56613 | Rps6ka4 | ribosomal protein S6 kinase, polypeptide 4 | 10090 | MGI:1930076 | Inparanoid, OMA, EggNOG |
| Rat | 361715 | Rps6ka4 | ribosomal protein S6 kinase A4 | 10116 | RGD:1307277 | Inparanoid, OMA, EggNOG |
| Dog | 612105 | RPS6KA4 | ribosomal protein S6 kinase A4 | 9615 | VGNC:45741 | Inparanoid, OMA |
| Horse | 100050279 | RPS6KA4 | ribosomal protein S6 kinase A4 | 9796 | VGNC:22560 | Inparanoid, OMA, EggNOG |
| Cow | 523746 | RPS6KA4 | ribosomal protein S6 kinase A4 | 9913 | VGNC:34143 | Inparanoid, OMA, EggNOG |
| Pig | 100626270 | RPS6KA4 | ribosomal protein S6 kinase A4 | 9823 | | Inparanoid, OMA |
| Anole lizard | 100552228 | rps6ka4 | ribosomal protein S6 kinase A4 | 28377 | | Inparanoid, OMA |
| Xenopus | 100486973 | rps6ka4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 | 8364 | XB-GENE-5759516 | Inparanoid, OMA, EggNOG |
| C. elegans | 172581 | rskn-2 | Putative ribosomal protein S6 kinase alpha-2 | 6239 | | Inparanoid, OMA |
| Fruitfly | 39241 | JIL-1 | JIL-1 kinase | 7227 | FBgn0020412 | Inparanoid, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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