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METTL3
| Description | N6-adenosine-methyltransferase catalytic subunit |
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Gene and Protein Information
| Gene ID | 56339 |
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| Uniprot Accession IDs | Q86U44 O14736 Q86V05 Q9HB32 |
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| Ensembl ID | ENSP00000298717 |
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| Symbol | MTA70 M6A IME4 Spo8 MT-A70 hMETTL3 |
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| Family | Belongs to the MT-A70-like family. |
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| Sequence | MSDTWSSIQAHKKQLDSLRERLQRRRKQDSGHLDLRNPEAALSPTFRSDSPVPTAPTSGGPKPSTASAVPELATDPELEKKLLHHLSDLALTLPTDAVSICLAISTPDAPATQDGVESLLQKFAAQELIEVKRGLLQDDAHPTLVTYADHSKLSAMMGAVAEKKGPGEVAGTVTGQKRRAEQDSTTVAAFASSLVSGLNSSASEPAKEPAKKSRKHAASDVDLEIESLLNQQSTKEQQSKKVSQEILELLNTTTAKEQSIVEKFRSRGRAQVQEFCDYGTKEECMKASDADRPCRKLHFRRIINKHTDESLGDCSFLNTCFHMDTCKYVHYEIDACMDSEAPGSKDHTPSQELALTQSVGGDSSADRLFPPQWICCDIRYLDVSILGKFAVVMADPPWDIHMELPYGTLTDDEMRRLNIPVLQDDGFLFLWVTGRAMELGRECLNLWGYERVDEIIWVKTNQLQRIIRTGRTGHWLNHGKEHCLVGVKGNPQGFNQGLDCDVIVAEVRSTSHKPDEIYGMIERLSPGTRKIELFGRPHNVQPNWITLGNQLDGIHLLDPDVVARFKQRYPDGIISKPKNL Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 452765 | METTL3 | methyltransferase like 3 | 9598 | VGNC:3382 | Inparanoid, OMA, EggNOG |
| Macaque | | SALL2 | spalt like transcription factor 2 [Source:HGNC Symbol;Acc:HGNC:10526] | 9544 | | OMA, EggNOG |
| Mouse | 56335 | Mettl3 | methyltransferase like 3 | 10090 | MGI:1927165 | Inparanoid, OMA, EggNOG |
| Rat | 361035 | Mettl3 | methyltransferase-like 3 | 10116 | RGD:1311750 | Inparanoid, OMA, EggNOG |
| Dog | 475404 | METTL3 | methyltransferase like 3 | 9615 | VGNC:43177 | Inparanoid, OMA, EggNOG |
| Horse | 100059413 | METTL3 | methyltransferase like 3 | 9796 | VGNC:20130 | Inparanoid, OMA, EggNOG |
| Cow | 540339 | METTL3 | methyltransferase like 3 | 9913 | VGNC:31412 | Inparanoid, OMA, EggNOG |
| Pig | 100513294 | METTL3 | methyltransferase like 3 | 9823 | | Inparanoid, OMA, EggNOG |
| Opossum | 100023433 | METTL3 | methyltransferase like 3 | 13616 | | Inparanoid, EggNOG |
| Anole lizard | 100557846 | mettl3 | methyltransferase like 3 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 549173 | mettl3 | methyltransferase like 3 | 8364 | XB-GENE-922807 | Inparanoid, OMA, EggNOG |
| Zebrafish | 100004398 | mettl3 | methyltransferase like 3 | 7955 | ZDB-GENE-030131-9498 | Inparanoid, OMA, EggNOG |
| Fruitfly | 42844 | Ime4 | Inducer of meiosis 4 | 7227 | FBgn0039139 | Inparanoid, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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