MAP3K9

DescriptionMitogen-activated protein kinase kinase kinase 9

Gene and Protein Information

Gene ID4293
Uniprot Accession IDs A3KN85 Q0D2G7 Q6EH31 Q9H2N5
Ensembl ID ENSP00000451263
Symbol MLK1 PRKE1 MLK1 MEKK9 PRKE1
FamilyBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Sequence
MEPSRALLGCLASAAAAAPPGEDGAGAGAEEEEEEEEEAAAAVGPGELGCDAPLPYWTAVFEYEAAGEDELTLRLGDVVEVLSKDSQVSGDEGWWTGQLNQRVGIFPSNYVTPRSAFSSRCQPGGEDPSCYPPIQLLEIDFAELTLEEIIGIGGFGKVYRAFWIGDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEPNLCLVMEFARGGPLNRVLSGKRIPPDILVNWAVQIARGMNYLHDEAIVPIIHRDLKSSNILILQKVENGDLSNKILKITDFGLAREWHRTTKMSAAGTYAWMAPEVIRASMFSKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMNKLALPIPSTCPEPFAKLMEDCWNPDPHSRPSFTNILDQLTTIEESGFFEMPKDSFHCLQDNWKHEIQEMFDQLRAKEKELRTWEEELTRAALQQKNQEELLRRREQELAEREIDILERELNIIIHQLCQEKPRVKKRKGKFRKSRLKLKDGNRISLPSDFQHKFTVQASPTMDKRKSLINSRSSPPASPTIIPRLRAIQLTPGESSKTWGRSSVVPKEEGEEEEKRAPKKKGRTWGPGTLGQKELASGDEGSPQRREKANGLSTPSESPHFHLGLKSLVDGYKQWSSSAPNLVKGPRSSPALPGFTSLMEMEDEDSEGPGSGESRLQHSPSQSYLCIPFPRGEDGDGPSSDGIHEEPTPVNSATSTPQLTPTNSLKRGGAHHRRCEVALLGCGAVLAATGLGFDLLEAGKCQLLPLEEPEPPAREEKKRREGLFQRSSRPRRSTSPPSRKLFKKEEPMLLLGDPSASLTLLSLSSISECNSTRSLLRSDSDEIVVYEMPVSPVEAPPLSPCTHNPLVNVRVERFKRDPNQSLTPTHVTLTTPSQPSSHRRTPSDGALKPETLLASRSPSSNGLSPSPGAGMLKTPSPSRDPGEFPRLPDPNVVFPPTPRRWNTQQDSTLERPKTLEFLPRPRPSANRQRLDPWWFVSPSHARSTSPANSSSTETPSNLDSCFASSSSTVEERPGLPALLPFQAGPLPPTERTLLDLDAEGQSQDSTVPLCRAELNTHRPAPYEIQQEFWS
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp467498MAP3K9mitogen-activated protein kinase kinase kinase 99598OMA, EggNOG
Macaque693835MAP3K9mitogen-activated protein kinase kinase kinase 99544Inparanoid, OMA, EggNOG
Mouse338372Map3k9mitogen-activated protein kinase kinase kinase 910090MGI:2449952Inparanoid, OMA, EggNOG
Rat500690Map3k9mitogen-activated protein kinase kinase kinase 910116RGD:1562149Inparanoid, OMA, EggNOG
Dog490765MAP3K9mitogen-activated protein kinase kinase kinase 99615VGNC:42980Inparanoid, OMA, EggNOG
Horse100054289MAP3K9mitogen-activated protein kinase kinase kinase 99796VGNC:19944Inparanoid, OMA, EggNOG
Cow538340MAP3K9mitogen-activated protein kinase kinase kinase 99913VGNC:31203Inparanoid, OMA, EggNOG
Opossum100020082MAP3K9mitogen-activated protein kinase kinase kinase 913616Inparanoid, EggNOG
Anole lizard100556486map3k9mitogen-activated protein kinase kinase kinase 928377Inparanoid, OMA
Xenopus100488949map3k9mitogen-activated protein kinase kinase kinase 98364XB-GENE-989075Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    MLK family    /    MLK subfamily    /    Mitogen-activated protein kinase kinase kinase 9

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source