CDC42BPB

DescriptionSerine/threonine-protein kinase MRCK beta

Gene and Protein Information

Gene ID9578
Uniprot Accession IDs A9JR72 Q2L7A5 Q86TJ1 Q9ULU5
Ensembl ID ENSP00000355237
Symbol KIAA1124 MRCKB
FamilyBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
Sequence
MSAKVRLKKLEQLLLDGPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAKPFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETACFREERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFYIGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTPDYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERFQFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPDVSSPSDTSNFDVDDDVLRNTEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSLKSIMQSNTLTKDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSNSNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESELEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKKLTAENEKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHWEAQIAEIIQWVSDEKDARGYLQALASKMTEELEALRSSSLGSRTLDPLWKVRRSQKLDMSARLELQSALEAEIRAKQLVQEELRKVKDANLTLESKLKDSEAKNRELLEEMEILKKKMEEKFRADTGLKLPDFQDSIFEYFNTAPLAHDLTFRTSSASEQETQAPKPEASPSMSVAASEQQEDMARPPQRPSAVPLPTTQALALAGPKPKAHQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFACHVSCKDGAPQVCPIPPEQSKRPLGVDVQRGIGTAYKGHVKVPKPTGVKKGWQRAYAVVCDCKLFLYDLPEGKSTQPGVIASQVLDLRDDEFSVSSVLASDVIHATRRDIPCIFRVTASLLGAPSKTSSLLILTENENEKRKWVGILEGLQSILHKNRLRNQVVHVPLEAYDSSLPLIKAILTAAIVDADRIAVGLEEGLYVIEVTRDVIVRAADCKKVHQIELAPREKIVILLCGRNHHVHLYPWSSLDGAEGSFDIKLPETKGCQLMATATLKRNSGTCLFVAVKRLILCYEIQRTKPFHRKFNEIVAPGSVQCLAVLRDRLCVGYPSGFCLLSIQGDGQPLNLVNPNDPSLAFLSQQSFDALCAVELESEEYLLCFSHMGLYVDPQGRRARAQELMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTMEWVQTIGLRRIRPLNSEGTLNLLNCEPPRLIYFKSKFSGAVLNVPDTSDNSKKQMLRTRSKRRFVFKVPEEERLQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAVPPSQEERPGPAPTNLARQPPSRNKPYISWPSSGGSEPSVTVPLRSMSDPDQDFDKEPDSDSTKHSTPSNSSNPSGPPSPNSPHRSQLPLEGLEQPACDT
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Macaque695720CDC42BPBCDC42 binding protein kinase beta9544Inparanoid, OMA
Mouse217866Cdc42bpbCDC42 binding protein kinase beta10090MGI:2136459Inparanoid, OMA, EggNOG
Rat113960Cdc42bpbCDC42 binding protein kinase beta10116RGD:621753Inparanoid, OMA, EggNOG
Dog490868CDC42BPBCDC42 binding protein kinase beta9615VGNC:38998Inparanoid, OMA, EggNOG
Horse100058888CDC42BPBCDC42 binding protein kinase beta9796VGNC:16297Inparanoid, OMA, EggNOG
Cow508226CDC42BPBCDC42 binding protein kinase beta9913VGNC:27070Inparanoid, OMA
Pig100156588CDC42BPBCDC42 binding protein kinase beta9823Inparanoid, OMA
Opossum100017279CDC42BPBCDC42 binding protein kinase beta13616Inparanoid, EggNOG
Platypus100076537CDC42BPBCDC42 binding protein kinase beta9258Inparanoid, OMA, EggNOG
Chicken423473CDC42BPBCDC42 binding protein kinase beta9031CGNC:8687Inparanoid, OMA, EggNOG
Anole lizard100557240cdc42bpbCDC42 binding protein kinase beta28377Inparanoid, OMA, EggNOG
Xenopus733471cdc42bpbCDC42 binding protein kinase beta8364XB-GENE-1005934Inparanoid, OMA
Zebrafish567039cdc42bpbCDC42 binding protein kinase beta (DMPK-like)7955ZDB-GENE-030131-3647Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    Serine/threonine-protein kinase mrck beta
protein    /    protein kinase    /    Serine/threonine-protein kinase mrck beta
protein    /    transferase    /    Serine/threonine-protein kinase mrck beta
protein    /    kinase    /    Serine/threonine-protein kinase mrck beta
DTO Classes
protein    /    Kinase    /    Protein kinase    /    AGC group    /    DMPK family    /    GEK subfamily    /    Serine/threonine-protein kinase mrck beta

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source