ABCC1

DescriptionMultidrug resistance-associated protein 1

Gene and Protein Information

Gene ID4363
Uniprot Accession IDs A3RJX2 C9JPJ4 O14819 O43333 P78419 Q59GI9 Q9UQ97 Q9UQ99 Q9UQA0
Ensembl ID ENSP00000382342
Symbol MRP MRP1 MRP ABCC GS-X MRP1 ABC29
FamilyBelongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Sequence
MALRGFCSADGSDPLWDWNVTWNTSNPDFTKCFQNTVLVWVPCFYLWACFPFYFLYLSRHDRGYIQMTPLNKTKTALGFLLWIVCWADLFYSFWERSRGIFLAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTALKEDAQVDLFRDITFYVYFSLLLIQLVLSCFSDRSPLFSETIHDPNPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLYKTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGTFTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIVMSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMENGMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNLVNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYREDLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIGLHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLDHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMAKDAGLV
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp453952ABCC1ATP binding cassette subfamily C member 19598VGNC:51175OMA, EggNOG
Macaque717857ABCC1ATP binding cassette subfamily C member 19544OMA, EggNOG
Mouse17250Abcc1ATP-binding cassette, sub-family C (CFTR/MRP), member 110090MGI:102676Inparanoid, OMA, EggNOG
Rat24565Abcc1ATP binding cassette subfamily C member 110116RGD:3112Inparanoid, OMA
Dog403453ABCC1ATP binding cassette subfamily C member 19615VGNC:54275Inparanoid, OMA, EggNOG
Horse791240ABCC1ATP binding cassette subfamily C member 19796VGNC:14913Inparanoid, OMA
Cow281588ABCC1ATP binding cassette subfamily C member 19913VGNC:25468Inparanoid, OMA
Opossum100023220ABCC1ATP binding cassette subfamily C member 113616Inparanoid, OMA, EggNOG
PlatypusABCC1ATP binding cassette subfamily C member 1 [Source:HGNC Symbol;Acc:HGNC:51]9258OMA, EggNOG
Chicken395416ABCC1ATP binding cassette subfamily C member 19031CGNC:49308Inparanoid, OMA, EggNOG
Xenopusabcc1ATP binding cassette subfamily C member 1 [Source:Xenbase;Acc:XB-GENE-960171]8364OMA, EggNOG
S.cerevisiae851713YCF1ATP-binding cassette glutathione S-conjugate transporter YCF14932S000002542OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    ATP-binding cassette (ABC) transporter    /    Multidrug resistance-associated protein 1
DTO Classes
protein    /    Transporter    /    ATP-binding cassette transporter family    /    ABCC subfamily    /    Multidrug resistance-associated protein 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source