MAP2K5

DescriptionDual specificity mitogen-activated protein kinase kinase 5

Gene and Protein Information

Gene ID5607
Uniprot Accession IDs B4DE43 Q92961 Q92962 MAP kinase kinase 5
Ensembl ID ENSP00000178640
Symbol MEK5 MKK5 PRKMK5 MEK5 MAPKK5 PRKMK5 HsT17454
FamilyBelongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Sequence
MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVCRALEERRSQQGPP
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp453532MAP2K5mitogen-activated protein kinase kinase 59598VGNC:7530OMA, EggNOG
Macaque711672MAP2K5mitogen-activated protein kinase kinase 59544Inparanoid, OMA, EggNOG
Mouse23938Map2k5mitogen-activated protein kinase kinase 510090MGI:1346345Inparanoid, OMA, EggNOG
Rat29568Map2k5mitogen activated protein kinase kinase 510116RGD:61890Inparanoid, OMA, EggNOG
Dog609559MAP2K5mitogen-activated protein kinase kinase 59615VGNC:42963Inparanoid, OMA, EggNOG
Horse100052849MAP2K5mitogen-activated protein kinase kinase 59796VGNC:19928Inparanoid, OMA, EggNOG
Cow100295732MAP2K5mitogen-activated protein kinase kinase 59913VGNC:31186Inparanoid, OMA, EggNOG
OpossumMAP2K5mitogen-activated protein kinase kinase 5 [Source:HGNC Symbol;Acc:HGNC:6845]13616Inparanoid, EggNOG
Platypus100085895MAP2K5mitogen-activated protein kinase kinase 59258Inparanoid, OMA, EggNOG
Chicken415557MAP2K5mitogen-activated protein kinase kinase 59031CGNC:50016Inparanoid, OMA, EggNOG
Anole lizard100562970map2k5mitogen-activated protein kinase kinase 528377Inparanoid, OMA, EggNOG
Xenopus549042map2k5mitogen-activated protein kinase kinase 58364XB-GENE-960353Inparanoid, OMA, EggNOG
Zebrafish100007679map2k5mitogen-activated protein kinase kinase 57955ZDB-GENE-030131-1517Inparanoid, OMA, EggNOG

Protein Classes

DTO Classes
protein    /    Kinase    /    Protein kinase    /    STE group    /    STE7 family    /    Dual specificity mitogen-activated protein kinase kinase 5

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source