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NLRP3
| Description | NACHT, LRR and PYD domains-containing protein 3 |
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Gene and Protein Information
| Gene ID | 114548 |
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| Uniprot Accession IDs | A0A024R5Q0 B2RC97 B7ZKS9 B7ZKT2 B7ZKT3 O75434 Q17RS2 Q59H68 Q5JQS8 Q5JQS9 Q6TG35 Q8TCW0 Q8TEU9 Q8WXH9 |
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| Ensembl ID | ENSP00000337383 |
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| Symbol | C1orf7 CIAS1 NALP3 PYPAF1 AII AVP FCU MWS FCAS KEFH CIAS1 FCAS1 NALP3 C1orf7 CLR1.1 DFNA34 PYPAF1 AGTAVPRL |
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| Family | Belongs to the NLRP family. |
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| Sequence | MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 469743 | NLRP3 | NLR family pyrin domain containing 3 | 9598 | VGNC:11565 | OMA, EggNOG |
| Macaque | 701278 | NLRP3 | NLR family pyrin domain containing 3 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 216799 | Nlrp3 | NLR family, pyrin domain containing 3 | 10090 | MGI:2653833 | Inparanoid, OMA, EggNOG |
| Rat | 287362 | Nlrp3 | NLR family, pyrin domain containing 3 | 10116 | RGD:1308314 | Inparanoid, OMA, EggNOG |
| Dog | 490576 | NLRP3 | NLR family pyrin domain containing 3 | 9615 | VGNC:43848 | Inparanoid, OMA |
| Cow | 538639 | NLRP3 | NLR family pyrin domain containing 3 | 9913 | VGNC:32117 | Inparanoid, OMA |
| Pig | 100514823 | NLRP3 | NLR family pyrin domain containing 3 | 9823 | | Inparanoid, OMA |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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