PCSK1

DescriptionNeuroendocrine convertase 1

Gene and Protein Information

Gene ID5122
Uniprot Accession IDs B7Z8T7 E9PHA1 P78478 Q92532 NEC 1
Ensembl ID ENSP00000308024
Symbol NEC1 PC1 PC3 NEC1 SPC3 BMIQ12
FamilyBelongs to the peptidase S8 family. Furin subfamily.
Sequence
MERRAWSLQCTAFVLFCAWCALNSAKAKRQFVNEWAAEIPGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALKANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRGVEKMVDPGEEQPTQENPKENTLVSKSPSSSSVGGRRDELEEGAPSQAMLRLLQSAFSKNSPPKQSPKKSPSAKLNIPYENFYEALEKLNKPSQLKDSEDSLYNDYVDVFYNTKPYKHRDDRLLQALVDILNEEN
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp461740PCSK1proprotein convertase subtilisin/kexin type 19598VGNC:4121OMA, EggNOG
Macaque699742PCSK1proprotein convertase subtilisin/kexin type 19544OMA, EggNOG
Mouse18548Pcsk1proprotein convertase subtilisin/kexin type 110090MGI:97511Inparanoid, OMA, EggNOG
Rat25204Pcsk1proprotein convertase subtilisin/kexin type 110116RGD:3272Inparanoid, OMA
Dog479149PCSK1proprotein convertase subtilisin/kexin type 19615VGNC:44320Inparanoid, OMA, EggNOG
Horse100064886PCSK1proprotein convertase subtilisin/kexin type 19796VGNC:21216Inparanoid, OMA, EggNOG
Cow281967PCSK1proprotein convertase subtilisin/kexin type 19913VGNC:32646Inparanoid, OMA, EggNOG
Pig397103PCSK1proprotein convertase subtilisin/kexin type 19823Inparanoid, OMA, EggNOG
Opossum100010673PCSK1proprotein convertase subtilisin/kexin type 113616Inparanoid, OMA, EggNOG
Chicken769230PCSK1proprotein convertase subtilisin/kexin type 19031CGNC:55088Inparanoid, OMA, EggNOG
Anole lizard100565158pcsk1proprotein convertase subtilisin/kexin type 128377Inparanoid, OMA, EggNOG
Xenopus100496933pcsk1proprotein convertase subtilisin/kexin type 18364XB-GENE-983314Inparanoid, OMA, EggNOG
Zebrafish100005716pcsk1proprotein convertase subtilisin/kexin type 17955ZDB-GENE-071009-1Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    serine protease    /    Neuroendocrine convertase 1
DTO Classes
protein    /    Enzyme    /    Protease    /    Serine protease    /    Neuroendocrine convertase 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source