NALCN

DescriptionSodium leak channel non-selective protein

Gene and Protein Information

Gene ID259232
Uniprot Accession IDs Q6P2S6 Q6ZMI7 Q8IZZ1 Q8TAH1
Ensembl ID ENSP00000251127
Symbol VGCNL1 IHPRF INNFD CanIon IHPRF1 VGCNL1 CLIFAHDD bA430M15.1
FamilyBelongs to the cation-nonselective channel family.
Sequence
MLKRKQSSRVEAQPVTDFGPDESLSDNADILWINKPWVHSLLRICAIISVISVCMNTPMTFEHYPPLQYVTFTLDTLLMFLYTAEMIAKMHIRGIVKGDSSYVKDRWCVFDGFMVFCLWVSLVLQVFEIADIVDQMSPWGMLRIPRPLIMIRAFRIYFRFELPRTRITNILKRSGEQIWSVSIFLLFFLLLYGILGVQMFGTFTYHCVVNDTKPGNVTWNSLAIPDTHCSPELEEGYQCPPGFKCMDLEDLGLSRQELGYSGFNEIGTSIFTVYEAASQEGWVFLMYRAIDSFPRWRSYFYFITLIFFLAWLVKNVFIAVIIETFAEIRVQFQQMWGSRSSTTSTATTQMFHEDAAGGWQLVAVDVNKPQGRAPACLQKMMRSSVFHMFILSMVTVDVIVAASNYYKGENFRRQYDEFYLAEVAFTVLFDLEALLKIWCLGFTGYISSSLHKFELLLVIGTTLHVYPDLYHSQFTYFQVLRVVRLIKISPALEDFVYKIFGPGKKLGSLVVFTASLLIVMSAISLQMFCFVEELDRFTTFPRAFMSMFQILTQEGWVDVMDQTLNAVGHMWAPVVAIYFILYHLFATLILLSLFVAVILDNLELDEDLKKLKQLKQSEANADTKEKLPLRLRIFEKFPNRPQMVKISKLPSDFTVPKIRESFMKQFIDRQQQDTCCLLRSLPTTSSSSCDHSKRSAIEDNKYIDQKLRKSVFSIRARNLLEKETAVTKILRACTRQRMLSGSFEGQPAKERSILSVQHHIRQERRSLRHGSNSQRISRGKSLETLTQDHSNTVRYRNAQREDSEIKMIQEKKEQAEMKRKVQEEELRENHPYFDKPLFIVGREHRFRNFCRVVVRARFNASKTDPVTGAVKNTKYHQLYDLLGLVTYLDWVMIIVTICSCISMMFESPFRRVMHAPTLQIAEYVFVIFMSIELNLKIMADGLFFTPTAVIRDFGGVMDIFIYLVSLIFLCWMPQNVPAESGAQLLMVLRCLRPLRIFKLVPQMRKVVRELFSGFKEIFLVSILLLTLMLVFASFGVQLFAGKLAKCNDPNIIRREDCNGIFRINVSVSKNLNLKLRPGEKKPGFWVPRVWANPRNFNFDNVGNAMLALFEVLSLKGWVEVRDVIIHRVGPIHGIYIHVFVFLGCMIGLTLFVGVVIANFNENKGTALLTVDQRRWEDLKSRLKIAQPLHLPPRPDNDGFRAKMYDITQHPFFKRTIALLVLAQSVLLSVKWDVEDPVTVPLATMSVVFTFIFVLEVTMKIIAMSPAGFWQSRRNRYDLLVTSLGVVWVVLHFALLNAYTYMMGACVIVFRFFSICGKHVTLKMLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVLFRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLLVAIIVENFSLFYSTEEDQLLSYNDLRHFQIIWNMVDDKREGVIPTFRVKFLLRLLRGRLEVDLDKDKLLFKHMCYEMERLHNGGDVTFHDVLSMLSYRSVDIRKSLQLEELLAREQLEYTIEEEVAKQTIRMWLKKCLKRIRAKQQQSCSIIHSLRESQQQELSRFLNPPSIETTQPSEDTNANSQDNSMQPETSSQQQLLSPTLSDRGGSRQDAADAGKPQRKFGQWRLPSAPKPISHSVSSVNLRFGGRTTMKSVVCKMNPMTDAASCGSEVKKWWTRQLTVESDESGDDLLDI
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp452643NALCNsodium leak channel, non-selective9598VGNC:13220OMA, EggNOG
Macaque106994360NALCNsodium leak channel, non-selective9544OMA, EggNOG
Mouse338370Nalcnsodium leak channel, non-selective10090MGI:2444306Inparanoid, OMA, EggNOG
Rat266760Nalcnsodium leak channel, non-selective10116RGD:628710Inparanoid, OMA, EggNOG
Dog485535NALCNsodium leak channel, non-selective9615VGNC:43613Inparanoid, OMA, EggNOG
Horse100062714NALCNsodium leak channel, non-selective9796VGNC:20553Inparanoid, OMA, EggNOG
Cow536103NALCNsodium leak channel, non-selective9913VGNC:31874Inparanoid, OMA, EggNOG
Opossum100019011NALCNsodium leak channel, non-selective13616Inparanoid, OMA, EggNOG
Platypus100083068NALCNsodium leak channel, non-selective9258Inparanoid, OMA, EggNOG
Chicken418770NALCNsodium leak channel, non-selective9031CGNC:12660Inparanoid, OMA, EggNOG
Xenopusnalcnsodium leak channel, non selective [Source:Xenbase;Acc:XB-GENE-1012705]8364OMA, EggNOG
Zebrafish548345nalcnsodium leak channel, non-selective7955ZDB-GENE-050410-12Inparanoid, OMA, EggNOG
C. elegans177379unc-77Uncharacterized protein6239Inparanoid, OMA

Protein Classes

DTO Classes
protein    /    Ion channel    /    Cation-nonselective channel family    /    Sodium leak channel non-selective protein

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source