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PCSK2
| Description | Neuroendocrine convertase 2 |
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Gene and Protein Information
| Gene ID | 5126 |
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| Uniprot Accession IDs | B1ANH9 B4DFQ3 Q14927 Q5JYQ1 Q8IWA8 Q9NQG3 Q9NUG1 Q9UJC6 NEC 2 |
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| Ensembl ID | ENSP00000262545 |
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| Symbol | NEC2 PC2 NEC2 SPC2 NEC 2 NEC-2 |
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| Family | Belongs to the peptidase S8 family. Furin subfamily. |
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| Sequence | MKGGCVSQWKAAAGFLFCVMVFASAERPVFTNHFLVELHKGGEDKARQVAAEHGFGVRKLPFAEGLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEIDINMNDPLFTKQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEWTLMLHGTQSAPYIDQVVRDYQSKLAMSKKEELEEELDEAVERSLKSILNKN Show more |
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
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| Chimp | 458106 | PCSK2 | proprotein convertase subtilisin/kexin type 2 | 9598 | VGNC:9940 | OMA, EggNOG |
| Macaque | 695730 | PCSK2 | proprotein convertase subtilisin/kexin type 2 | 9544 | | Inparanoid, OMA, EggNOG |
| Mouse | 18549 | Pcsk2 | proprotein convertase subtilisin/kexin type 2 | 10090 | MGI:97512 | Inparanoid, OMA, EggNOG |
| Rat | 25121 | Pcsk2 | proprotein convertase subtilisin/kexin type 2 | 10116 | RGD:3273 | Inparanoid, OMA, EggNOG |
| Dog | 485757 | PCSK2 | proprotein convertase subtilisin/kexin type 2 | 9615 | VGNC:44322 | Inparanoid, OMA, EggNOG |
| Horse | 100050755 | PCSK2 | proprotein convertase subtilisin/kexin type 2 | 9796 | VGNC:21217 | Inparanoid, OMA, EggNOG |
| Cow | 281968 | PCSK2 | proprotein convertase subtilisin/kexin type 2 | 9913 | VGNC:32648 | Inparanoid, OMA, EggNOG |
| Pig | 445533 | PCSK2 | proprotein convertase subtilisin/kexin type 2 | 9823 | | OMA, EggNOG |
| Opossum | 100033262 | PCSK2 | proprotein convertase subtilisin/kexin type 2 | 13616 | | Inparanoid, EggNOG |
| Platypus | | PCSK2 | proprotein convertase subtilisin/kexin type 2 [Source:HGNC Symbol;Acc:HGNC:8744] | 9258 | | OMA, EggNOG |
| Chicken | 395136 | PCSK2 | proprotein convertase subtilisin/kexin type 2 | 9031 | CGNC:49185 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100564235 | pcsk2 | proprotein convertase subtilisin/kexin type 2 | 28377 | | Inparanoid, OMA, EggNOG |
| Xenopus | 100036632 | pcsk2 | proprotein convertase subtilisin/kexin type 2 | 8364 | XB-GENE-960013 | Inparanoid, OMA, EggNOG |
| Zebrafish | 100004460 | pcsk2 | proprotein convertase subtilisin/kexin type 2 | 7955 | ZDB-GENE-090608-1 | Inparanoid, OMA |
| C. elegans | 179412 | egl-3 | Neuroendocrine convertase 2 | 6239 | | Inparanoid, OMA |
| Fruitfly | 43215 | amon | amontillado | 7227 | FBgn0023179 | Inparanoid, EggNOG |
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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