PDPK1

Description3-phosphoinositide-dependent protein kinase 1

Gene and Protein Information

Gene ID5170
Uniprot Accession IDs H0Y4Z0 Q59EH6 Q6FI20 Q8IV52 Q9BRD5 hPDK1
Ensembl ID ENSP00000344220
Symbol PDK1 PDK1 PDPK2 PDPK2P PRO0461
FamilyBelongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.
Sequence
MARTTSQLYDAVPIQSSVVLCSCPSPSMVRTQTESSTPPGIPGGSRQGPAMDGTAAEPRPGAGSLQHAQPPPQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRLDHPFFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFESVTWENLHQQTPPKLTAYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSSSHSLSASDTGLPQRSGSNIEQYIHDLDSNSFELDLQFSEDEKRLLLEKQAGGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEGPHLYYVDPVNKVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQEVWRQRYQSHPDAAVQ
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp467875PDPK13-phosphoinositide dependent protein kinase 19598VGNC:13762OMA, EggNOG
Mouse18607Pdpk13-phosphoinositide dependent protein kinase 110090MGI:1338068Inparanoid, OMA, EggNOG
Rat81745Pdpk13-phosphoinositide dependent protein kinase-110116RGD:620307Inparanoid, OMA, EggNOG
Dog479875PDPK13-phosphoinositide dependent protein kinase 19615VGNC:54055Inparanoid, OMA, EggNOG
HorsePDPK13-phosphoinositide dependent protein kinase 1 [Source:HGNC Symbol;Acc:HGNC:8816]9796OMA, EggNOG
Cow100138102PDPK13-phosphoinositide dependent protein kinase 19913Inparanoid, OMA, EggNOG
Opossum100018830LOC1000188303-phosphoinositide-dependent protein kinase 113616OMA, EggNOG
Chicken416588PDPK13-phosphoinositide dependent protein kinase 19031CGNC:50287Inparanoid, OMA
Anole lizard100559955pdpk13-phosphoinositide dependent protein kinase 128377Inparanoid, OMA, EggNOG
Xenopus779524pdpk13-phosphoinositide dependent protein kinase 18364XB-GENE-991549Inparanoid, OMA, EggNOG
Zebrafish403000pdpk1b3-phosphoinositide dependent protein kinase 1b7955ZDB-GENE-040426-1820Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    calcium-binding protein    /    non-receptor serine/threonine protein kinase    /    3-phosphoinositide-dependent protein kinase 1
protein    /    calcium-binding protein    /    transfer/carrier protein    /    3-phosphoinositide-dependent protein kinase 1
protein    /    calcium-binding protein    /    protein kinase    /    3-phosphoinositide-dependent protein kinase 1
protein    /    calcium-binding protein    /    calmodulin    /    3-phosphoinositide-dependent protein kinase 1
protein    /    calcium-binding protein    /    annexin    /    3-phosphoinositide-dependent protein kinase 1
protein    /    calcium-binding protein    /    transferase    /    3-phosphoinositide-dependent protein kinase 1
protein    /    calcium-binding protein    /    kinase    /    3-phosphoinositide-dependent protein kinase 1
DTO Classes
protein    /    Kinase    /    Protein kinase    /    AGC group    /    PDK1 family    /    PDK1 subfamily    /    3-phosphoinositide-dependent protein kinase 1

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source