CDKL5

DescriptionCyclin-dependent kinase-like 5

Gene and Protein Information

Gene ID6792
Uniprot Accession IDs G9B9X4 Q14198 Q5H985 Q8IYC7 Q9UJL6
Ensembl ID ENSP00000369325
Symbol STK9 ISSX STK9 EIEE2 CFAP247
FamilyBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Sequence
MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSAKRKPYHVESSTLSNRNQAGKSTALQSHHRSNSKDIQNLSVGLPRADEGLPANESFLNGNLAGASLSPLHTKTYQASSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFNIDPKPSEGPGTKYLKSNSRSQQNRHSFMESSQSKAGTLQPNEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQIAEPSTSRYFPSSCLDLNSPTSPTPTRHSDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARSSVKETSREGTSSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFFRSMKKKKKKSQTVPNSDSPDLLTLQKSIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLRKLLHLSSASNHPASSDPRFQPLTAQQTKNSFSEIRIHPLSQASGGSSNIRQEPAPKGRPALQLPDGGCDGRRQRHHSGPQDRRFMLRTTEQQGEYFCCGDPKKPHTPCVPNRALHRPISSPAPYPVLQVRGTSMCPTLQVRGTDAFSCPTQQSGFSFFVRHVMREALIHRAQVNQAALLTYHENAALTGK
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Homologous gene and protein info.
SpeciesGene IDGene SymbolNameTax IDOther Gene IDSources
Chimp473529CDKL5cyclin dependent kinase like 59598VGNC:6431OMA, EggNOG
Macaque693974CDKL5cyclin dependent kinase like 59544OMA, EggNOG
Mouse382253Cdkl5cyclin-dependent kinase-like 510090MGI:1278336Inparanoid, OMA, EggNOG
Rat100362725Cdkl5cyclin-dependent kinase-like 510116RGD:2324133Inparanoid, OMA, EggNOG
Dog491761CDKL5cyclin dependent kinase like 59615VGNC:39067Inparanoid, OMA, EggNOG
Horse100057902CDKL5cyclin dependent kinase like 59796VGNC:16362Inparanoid, OMA, EggNOG
CowCDKL5cyclin dependent kinase like 5 [Source:HGNC Symbol;Acc:HGNC:11411]9913OMA, EggNOG
Pig100623797CDKL5cyclin dependent kinase like 59823Inparanoid, OMA, EggNOG
Opossum100031465CDKL5cyclin dependent kinase like 513616Inparanoid, OMA, EggNOG
Platypus100083764CDKL5cyclin dependent kinase like 59258Inparanoid, OMA, EggNOG
Chicken428001CDKL5cyclin dependent kinase like 59031CGNC:12380Inparanoid, OMA, EggNOG
Anole lizard100556829cdkl5cyclin dependent kinase like 528377Inparanoid, OMA, EggNOG
Zebrafish559341cdkl5cyclin-dependent kinase-like 57955ZDB-GENE-081022-110Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    non-receptor serine/threonine protein kinase    /    Cyclin-dependent kinase-like 5
protein    /    protein kinase    /    Cyclin-dependent kinase-like 5
protein    /    non-receptor tyrosine protein kinase    /    Cyclin-dependent kinase-like 5
protein    /    transferase    /    Cyclin-dependent kinase-like 5
protein    /    kinase    /    Cyclin-dependent kinase-like 5
DTO Classes
protein    /    Kinase    /    Protein kinase    /    CMGC group    /    CDKL family    /    Cyclin-dependent kinase-like 5

Associated Recombinant Proteins

NameSpecification and purityExpression systemProtein labelActivityView Details

Associated Antibodies

NameSpecificationsSpecies reactivityspeciesApplicationView Details

Associated Approved Drugs

    Associated Active Ligands

      Associated Diseases

      NameDisease TypeMondoid

      Pathway

      Data SourceNameExplore more targetsExplore in Source