CDK8
| Description | Cyclin-dependent kinase 8 |
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Gene and Protein Information
| Gene ID | 1024 |
|---|---|
| Uniprot Accession IDs | Q5VUF3 Q6ISB5 |
| Ensembl ID | ENSP00000370938 |
| Symbol | K35 |
| Family | Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. |
| Sequence | MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 452501 | CDK8 | cyclin dependent kinase 8 | 9598 | VGNC:7829 | OMA, EggNOG |
| Macaque | 709761 | CDK8 | cyclin dependent kinase 8 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 264064 | Cdk8 | cyclin-dependent kinase 8 | 10090 | MGI:1196224 | Inparanoid, OMA, EggNOG |
| Dog | 486035 | CDK8 | cyclin dependent kinase 8 | 9615 | VGNC:39061 | Inparanoid, OMA |
| Horse | 100050819 | CDK8 | cyclin dependent kinase 8 | 9796 | VGNC:16356 | Inparanoid, OMA, EggNOG |
| Cow | 507149 | CDK8 | cyclin dependent kinase 8 | 9913 | VGNC:27135 | Inparanoid, OMA, EggNOG |
| Pig | 100739805 | CDK8 | cyclin dependent kinase 8 | 9823 | OMA, EggNOG | |
| Opossum | 100019463 | CDK8 | cyclin dependent kinase 8 | 13616 | Inparanoid, OMA, EggNOG | |
| Chicken | 428080 | CDK8 | cyclin dependent kinase 8 | 9031 | CGNC:12849 | Inparanoid, OMA |
| Anole lizard | 100554966 | cdk8 | cyclin dependent kinase 8 | 28377 | Inparanoid, OMA | |
| Xenopus | 394856 | cdk8 | cyclin-dependent kinase 8 | 8364 | XB-GENE-962267 | Inparanoid, OMA |
| Zebrafish | 373868 | cdk8 | cyclin-dependent kinase 8 | 7955 | ZDB-GENE-030903-2 | Inparanoid, OMA, EggNOG |
| C. elegans | 172677 | cdk-8 | Cyclin-dependent kinase 8 | 6239 | Inparanoid, OMA, EggNOG | |
| Fruitfly | 39157 | Cdk8 | Cyclin-dependent kinase 8 | 7227 | FBgn0015618 | OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / non-receptor serine/threonine protein kinase / Cyclin-dependent kinase 8
protein / protein kinase / Cyclin-dependent kinase 8
protein / non-receptor tyrosine protein kinase / Cyclin-dependent kinase 8
protein / transferase / Cyclin-dependent kinase 8
protein / kinase / Cyclin-dependent kinase 8
protein / non-receptor serine/threonine protein kinase / Cyclin-dependent kinase 8
protein / protein kinase / Cyclin-dependent kinase 8
protein / non-receptor tyrosine protein kinase / Cyclin-dependent kinase 8
protein / transferase / Cyclin-dependent kinase 8
protein / kinase / Cyclin-dependent kinase 8
DTO Classes
protein / Kinase / Protein kinase / CMGC group / CDK family / CDK8 subfamily / Cyclin-dependent kinase 8
protein / Kinase / Protein kinase / CMGC group / CDK family / CDK8 subfamily / Cyclin-dependent kinase 8
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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