CASP2
| Description | Caspase-2 |
|---|
Gene and Protein Information
| Gene ID | 835 |
|---|---|
| Uniprot Accession IDs | A8K5F9 D3DXD6 E9PDN0 P42576 Q59F21 Q7KZL6 Q86UJ3 Q9BUP7 Q9BZK9 Q9BZL0 CASP-2 |
| Ensembl ID | ENSP00000312664 |
| Symbol | ICH1 NEDD2 ICH1 NEDD2 CASP-2 NEDD-2 PPP1R57 |
| Family | Belongs to the peptidase C14A family. |
| Sequence | MAAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEMRELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDMLLTTLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPVCLQVKPCTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVEGAIYGVDGKLLQLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGKEKLPKMRLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDMHVADMLVKVNALIKDREGYAPGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT Show more |
Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 463804 | CASP2 | caspase 2 | 9598 | VGNC:4294 | OMA, EggNOG |
| Mouse | 12366 | Casp2 | caspase 2 | 10090 | MGI:97295 | Inparanoid, OMA, EggNOG |
| Rat | 64314 | Casp2 | caspase 2 | 10116 | RGD:69274 | Inparanoid, OMA, EggNOG |
| Dog | 482737 | CASP2 | caspase 2 | 9615 | VGNC:38733 | Inparanoid, OMA, EggNOG |
| Horse | 100050611 | CASP2 | caspase 2 | 9796 | VGNC:16067 | Inparanoid, OMA, EggNOG |
| Cow | 531419 | CASP2 | caspase 2 | 9913 | VGNC:26780 | Inparanoid, OMA, EggNOG |
| Pig | 100521118 | CASP2 | caspase 2 | 9823 | OMA, EggNOG | |
| Opossum | 100011923 | CASP2 | caspase 2 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | CASP2 | caspase 2 [Source:HGNC Symbol;Acc:HGNC:1503] | 9258 | OMA, EggNOG | ||
| Chicken | 395857 | CASP2 | caspase 2 | 9031 | CGNC:10898 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100567806 | casp2 | caspase 2 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 100486813 | casp2 | caspase 2 | 8364 | XB-GENE-482390 | Inparanoid, OMA, EggNOG |
| Zebrafish | 373118 | casp2 | caspase 2, apoptosis-related cysteine peptidase | 7955 | ZDB-GENE-030825-3 | Inparanoid, EggNOG |
| Fruitfly | 39173 | Dronc | Death regulator Nedd2-like caspase | 7227 | FBgn0026404 | OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / enzyme modulator / protease inhibitor / Caspase-2
protein / enzyme modulator / cysteine protease / Caspase-2
protein / enzyme modulator / protease / Caspase-2
protein / enzyme modulator / hydrolase / Caspase-2
protein / enzyme modulator / protease inhibitor / Caspase-2
protein / enzyme modulator / cysteine protease / Caspase-2
protein / enzyme modulator / protease / Caspase-2
protein / enzyme modulator / hydrolase / Caspase-2
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Activity | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | species | Application | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Disease Type | Mondoid |
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Pathway
| Data Source | Name | Explore more targets | Explore in Source |
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